Fertility drugs and cancer : a guideline
Copyright © 2016. Published by Elsevier Inc..
Methodological limitations in studying the association between the use of fertility drugs and cancer include the inherent increased risk of cancer in women who never conceive, the low incidence of most of these cancers, and that the age of diagnosis of cancer typically is many years after fertility drug use. Based on available data, there does not appear to be a meaningful increased risk of invasive ovarian cancer, breast cancer, or endometrial cancer following the use of fertility drugs. Several studies have shown a small increased risk of borderline ovarian tumors; however, there is insufficient consistent evidence that a particular fertility drug increases the risk of borderline ovarian tumors, and any absolute risk is small. Given the available literature, patients should be counseled that infertile women may be at an increased risk of invasive ovarian, endometrial, and breast cancer; however, use of fertility drugs does not appear to increase this risk.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2016 |
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Erschienen: |
2016 |
Enthalten in: |
Zur Gesamtaufnahme - volume:106 |
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Enthalten in: |
Fertility and sterility - 106(2016), 7 vom: 30. Dez., Seite 1617-1626 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Practice Committee of the American Society for Reproductive Medicine. Electronic address: ASRM@asrm.org [VerfasserIn] |
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Links: |
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Themen: |
Fertility Agents, Female |
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Anmerkungen: |
Date Completed 07.06.2017 Date Revised 07.06.2017 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1016/j.fertnstert.2016.08.035 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM26386975X |
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520 | |a Methodological limitations in studying the association between the use of fertility drugs and cancer include the inherent increased risk of cancer in women who never conceive, the low incidence of most of these cancers, and that the age of diagnosis of cancer typically is many years after fertility drug use. Based on available data, there does not appear to be a meaningful increased risk of invasive ovarian cancer, breast cancer, or endometrial cancer following the use of fertility drugs. Several studies have shown a small increased risk of borderline ovarian tumors; however, there is insufficient consistent evidence that a particular fertility drug increases the risk of borderline ovarian tumors, and any absolute risk is small. Given the available literature, patients should be counseled that infertile women may be at an increased risk of invasive ovarian, endometrial, and breast cancer; however, use of fertility drugs does not appear to increase this risk | ||
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700 | 1 | |a La Barbera, Andrew |e investigator |4 oth | |
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700 | 1 | |a Widra, Eric |e investigator |4 oth | |
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