Social connectedness is associated with fibrinogen level in a human social network

© 2016 The Author(s)..

Socially isolated individuals face elevated rates of illness and death. Conventional measures of social connectedness reflect an individual's perceived network and can be subject to bias and variation in reporting. In this study of a large human social network, we find that greater indegree, a sociocentric measure of friendship and familial ties identified by a subject's social connections rather than by the subject, predicts significantly lower concentrations of fibrinogen (a biomarker of inflammation and cardiac risk), after adjusting for demographics, education, medical history and known predictors of cardiac risk. The association between fibrinogen and social isolation, as measured by low indegree, is comparable to the effect of smoking, and greater than that of low education, a conventional measure of socioeconomic disadvantage. By contrast, outdegree, which reflects an individual's perceived connectedness, displays a significantly weaker association with fibrinogen concentrations.

Medienart:

E-Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:283

Enthalten in:

Proceedings. Biological sciences - 283(2016), 1837 vom: 31. Aug.

Sprache:

Englisch

Beteiligte Personen:

Kim, David A [VerfasserIn]
Benjamin, Emelia J [VerfasserIn]
Fowler, James H [VerfasserIn]
Christakis, Nicholas A [VerfasserIn]

Links:

Volltext

Themen:

9001-32-5
Fibrinogen
Journal Article
Social epidemiology
Social hierarchy
Social networks
Stress response

Anmerkungen:

Date Completed 11.12.2017

Date Revised 30.03.2022

published: Print

Citation Status MEDLINE

doi:

10.1098/rspb.2016.0958

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM263739392