Rapid Identification of OXA-48 and OXA-163 Subfamilies in Carbapenem-Resistant Gram-Negative Bacilli with a Novel Immunochromatographic Lateral Flow Assay

Copyright © 2016, American Society for Microbiology. All Rights Reserved..

We assessed a novel immunochromatographic lateral flow assay for direct identification of OXA-48-like carbapenemases and accurate differentiation of allele variants with distinct substrate profiles (OXA-48 or OXA-163 subfamilies). The assay allowed rapid (less than 4 min) and reliable direct confirmation of OXA-163- and/or OXA-48-like enzymes (with 100% sensitivity and 100% specificity) from cultured colonies that were recovered from both solid medium and spiked blood culture bottles.

Medienart:

E-Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:54

Enthalten in:

Journal of clinical microbiology - 54(2016), 11 vom: 15. Nov., Seite 2832-2836

Sprache:

Englisch

Beteiligte Personen:

Pasteran, Fernando [VerfasserIn]
Denorme, Laurence [VerfasserIn]
Ote, Isabelle [VerfasserIn]
Gomez, Sonia [VerfasserIn]
De Belder, Denise [VerfasserIn]
Glupczynski, Youri [VerfasserIn]
Bogaerts, Pierre [VerfasserIn]
Ghiglione, Barbara [VerfasserIn]
Power, Pablo [VerfasserIn]
Mertens, Pascal [VerfasserIn]
Corso, Alejandra [VerfasserIn]

Themen:

Beta-Lactamases
EC 3.5.2.6
Journal Article

Anmerkungen:

Date Completed 11.07.2017

Date Revised 12.01.2019

published: Print-Electronic

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM263532097