Effects of Renal Denervation Documented in the Austrian National Multicentre Renal Denervation Registry
Renal denervation (RDN) is a new procedure for treatment-resistant hypertensive patients. In order to monitor all procedures undergone in Austria, the Austrian Society of Hypertension established the investigator-initiated Austrian Transcatheter Renal Denervation (TREND) Registry. From April 2011 to September 2014, 407 procedures in 14 Austrian centres were recorded. At baseline, office and mean 24-h ambulatory blood pressure (ABP) were 171/94 and 151/89 mmHg, respectively, and patients were taking a median of 4 antihypertensive medications. Mean 24-h ABP changes after 2-6 weeks, 3, 6 and 12 months were -11/-6, -8/-4, -8/-5 and -10/-6 mmHg (p<0.05 at all measurements), respectively. The periprocedural complication rate was 2.5%. Incidence of long-term complications during follow-up (median 1 year) was 0.5%. Office BP and ABP responses showed only a weak correlation (Pearson coefficient 0.303). Based on the data from the TREND registry, ambulatory blood pressure monitoring in addition to office BP should be used for patient selection as well as for monitoring response to RDN. Furthermore, criteria for optimal patient selection are suggested.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2016 |
|---|---|
| Erschienen: |
2016 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
|---|---|
| Enthalten in: |
PloS one - 11(2016), 8 vom: 26., Seite e0161250 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Zweiker, David [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 02.08.2017 Date Revised 13.11.2018 published: Electronic-eCollection Citation Status MEDLINE |
|---|
| doi: |
10.1371/journal.pone.0161250 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM263476162 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM263476162 | ||
| 003 | DE-627 | ||
| 005 | 20231224204006.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1371/journal.pone.0161250 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0878.xml |
| 035 | |a (DE-627)NLM263476162 | ||
| 035 | |a (NLM)27529426 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Zweiker, David |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effects of Renal Denervation Documented in the Austrian National Multicentre Renal Denervation Registry |
| 264 | 1 | |c 2016 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 02.08.2017 | ||
| 500 | |a Date Revised 13.11.2018 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Renal denervation (RDN) is a new procedure for treatment-resistant hypertensive patients. In order to monitor all procedures undergone in Austria, the Austrian Society of Hypertension established the investigator-initiated Austrian Transcatheter Renal Denervation (TREND) Registry. From April 2011 to September 2014, 407 procedures in 14 Austrian centres were recorded. At baseline, office and mean 24-h ambulatory blood pressure (ABP) were 171/94 and 151/89 mmHg, respectively, and patients were taking a median of 4 antihypertensive medications. Mean 24-h ABP changes after 2-6 weeks, 3, 6 and 12 months were -11/-6, -8/-4, -8/-5 and -10/-6 mmHg (p<0.05 at all measurements), respectively. The periprocedural complication rate was 2.5%. Incidence of long-term complications during follow-up (median 1 year) was 0.5%. Office BP and ABP responses showed only a weak correlation (Pearson coefficient 0.303). Based on the data from the TREND registry, ambulatory blood pressure monitoring in addition to office BP should be used for patient selection as well as for monitoring response to RDN. Furthermore, criteria for optimal patient selection are suggested | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 700 | 1 | |a Lambert, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Steinwender, Clemens |e verfasserin |4 aut | |
| 700 | 1 | |a Weber, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Suppan, Markus |e verfasserin |4 aut | |
| 700 | 1 | |a Brussee, Helmut |e verfasserin |4 aut | |
| 700 | 1 | |a Koppelstätter, Christian |e verfasserin |4 aut | |
| 700 | 1 | |a Kerschbaum, Julia |e verfasserin |4 aut | |
| 700 | 1 | |a Watschinger, Bruno |e verfasserin |4 aut | |
| 700 | 1 | |a Hohenstein-Scheibenecker, Katharina |e verfasserin |4 aut | |
| 700 | 1 | |a Reindl-Schwaighofer, Roman |e verfasserin |4 aut | |
| 700 | 1 | |a Sturmberger, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Kindslehner, Claudia |e verfasserin |4 aut | |
| 700 | 1 | |a Weiss, Thomas Werner |e verfasserin |4 aut | |
| 700 | 1 | |a Rohla, Miklos |e verfasserin |4 aut | |
| 700 | 1 | |a Gruener, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Maister, Petra |e verfasserin |4 aut | |
| 700 | 1 | |a Auer, Johann |e verfasserin |4 aut | |
| 700 | 1 | |a Dechant, Cornelia |e verfasserin |4 aut | |
| 700 | 1 | |a Sykora, Josef |e verfasserin |4 aut | |
| 700 | 1 | |a Krismer, Christoph |e verfasserin |4 aut | |
| 700 | 1 | |a Glaser, Stefan |e verfasserin |4 aut | |
| 700 | 1 | |a Zweiker, Robert |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t PloS one |d 2006 |g 11(2016), 8 vom: 26., Seite e0161250 |w (DE-627)NLM167327399 |x 1932-6203 |7 nnns |
| 773 | 1 | 8 | |g volume:11 |g year:2016 |g number:8 |g day:26 |g pages:e0161250 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1371/journal.pone.0161250 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 11 |j 2016 |e 8 |b 26 |h e0161250 | ||