A pioneer experience in Malaysia on In-house Radio-labelling of (131)I-rituximab in the treatment of Non-Hodgkin's Lymphoma and a case report of high dose (131)I-rituximab-BEAM conditioning autologous transplant

Copyright © 2016 Elsevier Ltd. All rights reserved..

Radioimmunotherapy is an established treatment modality in Non-Hodgkin's lymphoma. The only two commercially available radioimmunotherapies - (90)Y-ibritumomab tiuxetan is expensive and (131)I-tositumomab has been discontinued from commercial production. In resource limited environment, self-labelling (131)I-rituximab might be the only viable practical option. We reported our pioneer experience in Malaysia on self-labelling (131)I-rituximab, substituting autologous haematopoietic stem cell transplantation (HSCT) and a patient, the first reported case, received high dose (131)I-rituximab (6000MBq/163mCi) combined with BEAM conditioning for autologous HSCT.

Medienart:

E-Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:116

Enthalten in:

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine - 116(2016) vom: 21. Okt., Seite 13-21

Sprache:

Englisch

Beteiligte Personen:

Kuan, Jew Win [VerfasserIn]
Law, Chiong Soon [VerfasserIn]
Wong, Xiang Qi [VerfasserIn]
Ko, Ching Tiong [VerfasserIn]
Awang, Zool Hilmi [VerfasserIn]
Chew, Lee Ping [VerfasserIn]
Chang, Kian Meng [VerfasserIn]

Links:

Volltext

Themen:

(131)I-rituximab
131I-rituximab
4F4X42SYQ6
Antibodies, Monoclonal, Murine-Derived
Case Reports
Iodine-131
Journal Article
K2I4B6I9L1
Non-Hodgkin's lymphoma
Radioimmunotherapy
Radiopharmaceuticals
Rituximab

Anmerkungen:

Date Completed 07.02.2018

Date Revised 10.12.2019

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.apradiso.2016.07.016

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM262945045