Vitamin D and chronic diseases : the current state of the art
The objective was to provide the current state of the art regarding the role of vitamin D in chronic diseases (osteoporosis, cancer, cardiovascular diseases, dementia, autism, type 1 and type 2 diabetes mellitus, male and female fertility). The document was drawn up by panelists that provided their contribution according to their own scientific expertise. Each scientific expert supplied a first draft manuscript on a specific aspect of the document's topic that was subjected to voting by all experts as "yes" (agreement with the content and/or wording) or "no" (disagreement). The adopted rule was that statements supported by ≥75 % of votes would be immediately accepted, while those with <25 % would be rejected outright. Others would be subjected to further discussion and subsequent voting, where ≥67 % support or, in an eventual third round, a majority of ≥50 % would be needed. This document finds that the current evidence support a role for vitamin D in bone health but not in other health conditions. However, subjects with vitamin D deficiency have been found to be at high risk of developing chronic diseases. Therefore, although at the present time there is not sufficient evidence to recommend vitamin D supplementation as treatment of chronic diseases, the treatment of vitamin D deficiency should be desiderable in order to reduce the risk of developing chronic diseases.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:91 |
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| Enthalten in: |
Archives of toxicology - 91(2017), 1 vom: 17. Jan., Seite 97-107 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Muscogiuri, Giovanna [VerfasserIn] |
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| Links: |
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| Themen: |
1406-16-2 |
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| Anmerkungen: |
Date Completed 07.03.2017 Date Revised 17.08.2017 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00204-016-1804-x |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM262503700 |
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| 500 | |a Date Revised 17.08.2017 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The objective was to provide the current state of the art regarding the role of vitamin D in chronic diseases (osteoporosis, cancer, cardiovascular diseases, dementia, autism, type 1 and type 2 diabetes mellitus, male and female fertility). The document was drawn up by panelists that provided their contribution according to their own scientific expertise. Each scientific expert supplied a first draft manuscript on a specific aspect of the document's topic that was subjected to voting by all experts as "yes" (agreement with the content and/or wording) or "no" (disagreement). The adopted rule was that statements supported by ≥75 % of votes would be immediately accepted, while those with <25 % would be rejected outright. Others would be subjected to further discussion and subsequent voting, where ≥67 % support or, in an eventual third round, a majority of ≥50 % would be needed. This document finds that the current evidence support a role for vitamin D in bone health but not in other health conditions. However, subjects with vitamin D deficiency have been found to be at high risk of developing chronic diseases. Therefore, although at the present time there is not sufficient evidence to recommend vitamin D supplementation as treatment of chronic diseases, the treatment of vitamin D deficiency should be desiderable in order to reduce the risk of developing chronic diseases | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Autism | |
| 650 | 4 | |a Cancer | |
| 650 | 4 | |a Cardiovascular diseases | |
| 650 | 4 | |a Dementia | |
| 650 | 4 | |a Diabetes mellitus | |
| 650 | 4 | |a Endometriosis | |
| 650 | 4 | |a Environment | |
| 650 | 4 | |a Fertility | |
| 650 | 4 | |a Hypogonadism | |
| 650 | 4 | |a Lifestyle | |
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| 700 | 1 | |a Boucher, Barbara J |e verfasserin |4 aut | |
| 700 | 1 | |a Cannell, John J |e verfasserin |4 aut | |
| 700 | 1 | |a Foresta, Carlo |e verfasserin |4 aut | |
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| 700 | 1 | |a Kotsa, Kalliopi |e verfasserin |4 aut | |
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| 700 | 1 | |a Tirabassi, Giacomo |e verfasserin |4 aut | |
| 700 | 1 | |a Colao, Annamaria |e verfasserin |4 aut | |
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