Sixteen-year follow-up of hyperopic laser in situ keratomileusis
Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved..
PURPOSE: To assess the long-term efficacy and safety of hyperopic laser in situ keratomileusis (LASIK).
SETTING: Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom.
DESIGN: Prospective cohort study.
METHODS: Hyperopic LASIK was performed using a mechanical microkeratome, an optical zone of 6.5 mm, and a blend zone of 1.5 mm. Simple hyperopia was treated.
RESULTS: The mean patient age was 51.6 years (range 34 to 60 years). Preoperatively, the mean spherical equivalent (SE) was +3.74 diopters (D) (range +1.25 to +6.50 D). The mean attempted correction was +3.64 D (range +1.5 to +6.0 D). The mean follow-up was 16.5 years. The mean SE was +0.28 D (range -1.0 to +1.5 D) at 12 months, +0.84 D (range -0.75 to +3.35 D) at 5 years, and +1.74 D (range -0.75 to +4.13 D) at 16 years, representing an increase in hyperopia of +1.47 D ± 1.43 (SD) between 1 year and 16 years (P < .0001) and of +1.13 ± 0.8 D between 5 years and 16 years (P < .03). The uncorrected distance visual acuity improved at 16 years (P < .0001); corrected distance visual acuity (CDVA) was unchanged (P < .2). The efficacy index was 0.5 and the safety index, 1.09. One eye (3%) lost 2 lines of CDVA. Keratometry remained stable between 1 year and 16 years (P < 1.0). Four eyes (12%) had cataract surgery, and 2 (6%) had laser iridotomy. There was no ectasia.
CONCLUSIONS: After hyperopic LASIK, an increase in hyperopia occurred between 1 and 5 years and 16 years. At 16 years, efficacy was limited but with no sight-threatening complications.
FINANCIAL DISCLOSURES: Dr. Marshall was a consultant to Summit Technology, Inc. Dr. O'Brart holds a noncommercial research grant from Alcon Laboratories, Inc. None of the other authors has a financial or proprietary interest in any material or method mentioned.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2016 |
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Erschienen: |
2016 |
Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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Enthalten in: |
Journal of cataract and refractive surgery - 42(2016), 5 vom: 01. Mai, Seite 717-24 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Dave, Reena [VerfasserIn] |
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Anmerkungen: |
Date Completed 09.10.2018 Date Revised 08.04.2022 published: Print Citation Status MEDLINE |
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doi: |
10.1016/j.jcrs.2016.03.028 |
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funding: |
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PPN (Katalog-ID): |
NLM260999512 |
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500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved. | ||
520 | |a PURPOSE: To assess the long-term efficacy and safety of hyperopic laser in situ keratomileusis (LASIK) | ||
520 | |a SETTING: Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom | ||
520 | |a DESIGN: Prospective cohort study | ||
520 | |a METHODS: Hyperopic LASIK was performed using a mechanical microkeratome, an optical zone of 6.5 mm, and a blend zone of 1.5 mm. Simple hyperopia was treated | ||
520 | |a RESULTS: The mean patient age was 51.6 years (range 34 to 60 years). Preoperatively, the mean spherical equivalent (SE) was +3.74 diopters (D) (range +1.25 to +6.50 D). The mean attempted correction was +3.64 D (range +1.5 to +6.0 D). The mean follow-up was 16.5 years. The mean SE was +0.28 D (range -1.0 to +1.5 D) at 12 months, +0.84 D (range -0.75 to +3.35 D) at 5 years, and +1.74 D (range -0.75 to +4.13 D) at 16 years, representing an increase in hyperopia of +1.47 D ± 1.43 (SD) between 1 year and 16 years (P < .0001) and of +1.13 ± 0.8 D between 5 years and 16 years (P < .03). The uncorrected distance visual acuity improved at 16 years (P < .0001); corrected distance visual acuity (CDVA) was unchanged (P < .2). The efficacy index was 0.5 and the safety index, 1.09. One eye (3%) lost 2 lines of CDVA. Keratometry remained stable between 1 year and 16 years (P < 1.0). Four eyes (12%) had cataract surgery, and 2 (6%) had laser iridotomy. There was no ectasia | ||
520 | |a CONCLUSIONS: After hyperopic LASIK, an increase in hyperopia occurred between 1 and 5 years and 16 years. At 16 years, efficacy was limited but with no sight-threatening complications | ||
520 | |a FINANCIAL DISCLOSURES: Dr. Marshall was a consultant to Summit Technology, Inc. Dr. O'Brart holds a noncommercial research grant from Alcon Laboratories, Inc. None of the other authors has a financial or proprietary interest in any material or method mentioned | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
700 | 1 | |a O'Brart, David P S |e verfasserin |4 aut | |
700 | 1 | |a Wagh, Vijay K |e verfasserin |4 aut | |
700 | 1 | |a Lim, Wei S |e verfasserin |4 aut | |
700 | 1 | |a Patel, Parul |e verfasserin |4 aut | |
700 | 1 | |a Lee, Jennifer |e verfasserin |4 aut | |
700 | 1 | |a Marshall, John |e verfasserin |4 aut | |
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