Cross-sectional Imaging Review of Tuberous Sclerosis
Copyright © 2016 Elsevier Inc. All rights reserved..
Tuberous sclerosis complex (TSC) is a multisystem, genetic disorder characterized by development of hamartomas in the brain, abdomen, and thorax. It results from a mutation in one of 2 tumor suppressor genes that activates the mammalian target of rapamycin pathway. This article discusses the origins of the disorder, the recently updated criteria for the diagnosis of TSC, and the cross-sectional imaging findings and recommendations for surveillance. Familiarity with the diverse radiological features facilitates diagnosis and helps in treatment planning and monitoring response to treatment of this multisystem disorder.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2016 |
|---|---|
| Erschienen: |
2016 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:54 |
|---|---|
| Enthalten in: |
Radiologic clinics of North America - 54(2016), 3 vom: 15. Mai, Seite 423-40 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Krishnan, Anant [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Angiomyolipoma |
|---|
| Anmerkungen: |
Date Completed 23.01.2017 Date Revised 23.01.2017 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.rcl.2015.12.003 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM260107697 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM260107697 | ||
| 003 | DE-627 | ||
| 005 | 20231224192658.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2016 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.rcl.2015.12.003 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0867.xml |
| 035 | |a (DE-627)NLM260107697 | ||
| 035 | |a (NLM)27153781 | ||
| 035 | |a (PII)S0033-8389(15)00237-7 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Krishnan, Anant |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Cross-sectional Imaging Review of Tuberous Sclerosis |
| 264 | 1 | |c 2016 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 23.01.2017 | ||
| 500 | |a Date Revised 23.01.2017 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2016 Elsevier Inc. All rights reserved. | ||
| 520 | |a Tuberous sclerosis complex (TSC) is a multisystem, genetic disorder characterized by development of hamartomas in the brain, abdomen, and thorax. It results from a mutation in one of 2 tumor suppressor genes that activates the mammalian target of rapamycin pathway. This article discusses the origins of the disorder, the recently updated criteria for the diagnosis of TSC, and the cross-sectional imaging findings and recommendations for surveillance. Familiarity with the diverse radiological features facilitates diagnosis and helps in treatment planning and monitoring response to treatment of this multisystem disorder | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Angiomyolipoma | |
| 650 | 4 | |a Lymphangioleiomyomatosis | |
| 650 | 4 | |a MR imaging | |
| 650 | 4 | |a Subependymal giant cell astrocytoma (SEGA) | |
| 650 | 4 | |a Tuber | |
| 650 | 4 | |a Tuberous sclerosis | |
| 650 | 4 | |a mTOR | |
| 700 | 1 | |a Kaza, Ravi K |e verfasserin |4 aut | |
| 700 | 1 | |a Vummidi, Dharshan R |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Radiologic clinics of North America |d 1963 |g 54(2016), 3 vom: 15. Mai, Seite 423-40 |w (DE-627)NLM000103411 |x 1557-8275 |7 nnns |
| 773 | 1 | 8 | |g volume:54 |g year:2016 |g number:3 |g day:15 |g month:05 |g pages:423-40 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.rcl.2015.12.003 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 54 |j 2016 |e 3 |b 15 |c 05 |h 423-40 | ||