Eighteen-year follow-up of hyperopic photorefractive keratectomy
Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved..
PURPOSE: To investigate the long-term efficacy of hyperopic photorefractive keratectomy (PRK).
SETTING: University Hospital, London, United Kingdom.
DESIGN: Prospective case series.
METHODS: Patients with a follow-up of 18 years ± 0.7 (SD) attended for examination. All had spherical corrections with a 6.5 mm optical zone and 1.5 mm blend zone.
RESULTS: Twenty-five patients (45 eyes) were included. The mean preoperative spherical equivalent (SE) refractive error was +4.11 ± 1.8 diopters (D) (range +1.125 to +7.25 D). Between 1 year and 18 years, in eyes that had no cataract surgery (n = 34), there was a +1.14 ± 1.48 D increase in the mean SE (P < .0002). The increase between 7.5 years and 18.0 years did not reach clinical significance (P = .1). Uncorrected distance visual acuity improved at 18 years (P < .02). Corrected distance visual acuity (CDVA) was reduced (P < .001). The efficacy index was 0.47, and the safety index was 0.83. Six eyes (18%) lost 2 lines of CDVA, of which 4 eyes had preexisting cataract. Keratometry remained stable between 1 year and 18 years (P = .2). Forty percent still had traces of peripheral haze, and 4 (9%) had Salzmann-like changes. Eleven eyes (24%) had cataract surgery and 4 (9%) had laser iridotomy. There was no evidence of ectasia.
CONCLUSIONS: Hyperopic PRK showed an increase in hyperopic SE between 1.0 year and 7.5 years but was generally stable thereafter. The efficacy was limited. Peripheral haze was evident in 40% of cases with Salzmann-like changes in some. Ocular comorbidity in relationship to cataract was common and reduced CDVA.
FINANCIAL DISCLOSURE: Dr. Marshall was a consultant to Summit Technology, Inc. No author has a financial or proprietary interest in any material or method mentioned.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2016 |
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Erschienen: |
2016 |
Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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Enthalten in: |
Journal of cataract and refractive surgery - 42(2016), 2 vom: 29. Feb., Seite 258-66 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Wagh, Vijay K [VerfasserIn] |
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Anmerkungen: |
Date Completed 19.10.2016 Date Revised 30.03.2022 published: Print Citation Status MEDLINE |
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doi: |
10.1016/j.jcrs.2015.09.025 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM258900296 |
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520 | |a Copyright © 2016 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved. | ||
520 | |a PURPOSE: To investigate the long-term efficacy of hyperopic photorefractive keratectomy (PRK) | ||
520 | |a SETTING: University Hospital, London, United Kingdom | ||
520 | |a DESIGN: Prospective case series | ||
520 | |a METHODS: Patients with a follow-up of 18 years ± 0.7 (SD) attended for examination. All had spherical corrections with a 6.5 mm optical zone and 1.5 mm blend zone | ||
520 | |a RESULTS: Twenty-five patients (45 eyes) were included. The mean preoperative spherical equivalent (SE) refractive error was +4.11 ± 1.8 diopters (D) (range +1.125 to +7.25 D). Between 1 year and 18 years, in eyes that had no cataract surgery (n = 34), there was a +1.14 ± 1.48 D increase in the mean SE (P < .0002). The increase between 7.5 years and 18.0 years did not reach clinical significance (P = .1). Uncorrected distance visual acuity improved at 18 years (P < .02). Corrected distance visual acuity (CDVA) was reduced (P < .001). The efficacy index was 0.47, and the safety index was 0.83. Six eyes (18%) lost 2 lines of CDVA, of which 4 eyes had preexisting cataract. Keratometry remained stable between 1 year and 18 years (P = .2). Forty percent still had traces of peripheral haze, and 4 (9%) had Salzmann-like changes. Eleven eyes (24%) had cataract surgery and 4 (9%) had laser iridotomy. There was no evidence of ectasia | ||
520 | |a CONCLUSIONS: Hyperopic PRK showed an increase in hyperopic SE between 1.0 year and 7.5 years but was generally stable thereafter. The efficacy was limited. Peripheral haze was evident in 40% of cases with Salzmann-like changes in some. Ocular comorbidity in relationship to cataract was common and reduced CDVA | ||
520 | |a FINANCIAL DISCLOSURE: Dr. Marshall was a consultant to Summit Technology, Inc. No author has a financial or proprietary interest in any material or method mentioned | ||
650 | 4 | |a Journal Article | |
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700 | 1 | |a O'Brart, David P S |e verfasserin |4 aut | |
700 | 1 | |a Lim, Wei S |e verfasserin |4 aut | |
700 | 1 | |a Patel, Parul |e verfasserin |4 aut | |
700 | 1 | |a Tam, Connan |e verfasserin |4 aut | |
700 | 1 | |a Lee, Jennifer |e verfasserin |4 aut | |
700 | 1 | |a Marshall, John |e verfasserin |4 aut | |
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