Pulmonary Nodule Detection in CT Images : False Positive Reduction Using Multi-View Convolutional Networks

We propose a novel Computer-Aided Detection (CAD) system for pulmonary nodules using multi-view convolutional networks (ConvNets), for which discriminative features are automatically learnt from the training data. The network is fed with nodule candidates obtained by combining three candidate detectors specifically designed for solid, subsolid, and large nodules. For each candidate, a set of 2-D patches from differently oriented planes is extracted. The proposed architecture comprises multiple streams of 2-D ConvNets, for which the outputs are combined using a dedicated fusion method to get the final classification. Data augmentation and dropout are applied to avoid overfitting. On 888 scans of the publicly available LIDC-IDRI dataset, our method reaches high detection sensitivities of 85.4% and 90.1% at 1 and 4 false positives per scan, respectively. An additional evaluation on independent datasets from the ANODE09 challenge and DLCST is performed. We showed that the proposed multi-view ConvNets is highly suited to be used for false positive reduction of a CAD system.

Medienart:

E-Artikel

Erscheinungsjahr:

2016

Erschienen:

2016

Enthalten in:

Zur Gesamtaufnahme - volume:35

Enthalten in:

IEEE transactions on medical imaging - 35(2016), 5 vom: 05. Mai, Seite 1160-1169

Sprache:

Englisch

Beteiligte Personen:

Setio, Arnaud Arindra Adiyoso [VerfasserIn]
Ciompi, Francesco [VerfasserIn]
Litjens, Geert [VerfasserIn]
Gerke, Paul [VerfasserIn]
Jacobs, Colin [VerfasserIn]
van Riel, Sarah J [VerfasserIn]
Wille, Mathilde Marie Winkler [VerfasserIn]
Naqibullah, Matiullah [VerfasserIn]
Sanchez, Clara I [VerfasserIn]
van Ginneken, Bram [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 28.06.2017

Date Revised 30.03.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1109/TMI.2016.2536809

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM258215526