Glycolipids synthesis : improved hydrazinolysis conditions for preparation of 1,2-polyunsaturated fatty acyl-β-monogalactosyl-glycerols
Copyright © 2016 Elsevier Ltd. All rights reserved..
The investigation is related to the development of a general strategy for the synthesis of glycolipids including analogs bearing polyunsaturated fatty acids. In particular, here we report exceptionally mild and selective conditions to remove acetate protecting groups from glyceroglycolipids by hydrazinolysis. Synthetic 1,2-O-di-arachidonoyl-3-O-β-galactosyl-glycerol was used as representative of polyunsaturated β-galactosyl-di-acyl-glycerols due to its reactivity under the conditions usually employed in literature.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2016 |
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| Erschienen: |
2016 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:424 |
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| Enthalten in: |
Carbohydrate research - 424(2016) vom: 07. Apr., Seite 21-3 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Pagano, Dario [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 13.12.2016 Date Revised 30.12.2016 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.carres.2016.02.005 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM257902716 |
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| 500 | |a Date Revised 30.12.2016 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2016 Elsevier Ltd. All rights reserved. | ||
| 520 | |a The investigation is related to the development of a general strategy for the synthesis of glycolipids including analogs bearing polyunsaturated fatty acids. In particular, here we report exceptionally mild and selective conditions to remove acetate protecting groups from glyceroglycolipids by hydrazinolysis. Synthetic 1,2-O-di-arachidonoyl-3-O-β-galactosyl-glycerol was used as representative of polyunsaturated β-galactosyl-di-acyl-glycerols due to its reactivity under the conditions usually employed in literature | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Acetate | |
| 650 | 4 | |a Bioactive lipids | |
| 650 | 4 | |a Galactolipids | |
| 650 | 4 | |a Organic synthesis | |
| 650 | 4 | |a Protecting group | |
| 650 | 4 | |a Synthetic method | |
| 650 | 7 | |a Diglycerides |2 NLM | |
| 650 | 7 | |a Fatty Acids, Unsaturated |2 NLM | |
| 650 | 7 | |a Glycolipids |2 NLM | |
| 650 | 7 | |a Glycerol |2 NLM | |
| 650 | 7 | |a PDC6A3C0OX |2 NLM | |
| 700 | 1 | |a Cutignano, Adele |e verfasserin |4 aut | |
| 700 | 1 | |a Manzo, Emiliano |e verfasserin |4 aut | |
| 700 | 1 | |a Tinto, Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Fontana, Angelo |e verfasserin |4 aut | |
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