Primary Liver Sinusoidal Non-Hodgkin's Lymphoma Presenting as Acute Liver Failure
We describe a case of a middle-aged woman, who presented to us with fever, anorexia, abdominal distension from a massive hepatomegaly, low hemoglobin, and acute liver failure. A liver biopsy revealed B cell non-Hodgkin's lymphoma predominantly in the sinusoids with CD10, CD20, and Bcl-2 positive on immunohistochemistry. She initially responded well to chemotherapy but succumbed 6 months later to the recurrence of disease. Sinusoidal non-Hodgkin's lymphoma of the liver should be considered in the differential diagnosis of a patient with large hepatomegaly presenting with acute liver failure.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2015 |
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Erschienen: |
2015 |
Enthalten in: |
Zur Gesamtaufnahme - volume:5 |
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Enthalten in: |
Journal of clinical and experimental hepatology - 5(2015), 4 vom: 28. Dez., Seite 341-3 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Nagral, Aabha [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 22.02.2016 Date Revised 30.09.2020 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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doi: |
10.1016/j.jceh.2015.10.007 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM257700668 |
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520 | |a We describe a case of a middle-aged woman, who presented to us with fever, anorexia, abdominal distension from a massive hepatomegaly, low hemoglobin, and acute liver failure. A liver biopsy revealed B cell non-Hodgkin's lymphoma predominantly in the sinusoids with CD10, CD20, and Bcl-2 positive on immunohistochemistry. She initially responded well to chemotherapy but succumbed 6 months later to the recurrence of disease. Sinusoidal non-Hodgkin's lymphoma of the liver should be considered in the differential diagnosis of a patient with large hepatomegaly presenting with acute liver failure | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a AFP, alpha feto protein | |
650 | 4 | |a ALT, alanine aminotransferase | |
650 | 4 | |a AST, aspartate aminotransferase | |
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650 | 4 | |a Bcl 2, B cell lymphoma 2 | |
650 | 4 | |a CD, cluster differentiation | |
650 | 4 | |a CECT, contrast enhanced computed tomography | |
650 | 4 | |a CHOP, cyclophosphamide hydroxydaunorubicin (adriyamycin) oncovin (vincristine) prednisolone | |
650 | 4 | |a CK, cyto keratin | |
650 | 4 | |a HBsAg, hepatitis B surface antigen | |
650 | 4 | |a HCV, hepatitis C virus | |
650 | 4 | |a HIV, human immunodeficiency virus | |
650 | 4 | |a IgM, immunoglobulin M | |
650 | 4 | |a NHL, non-Hodgkins lymphoma | |
650 | 4 | |a PET CT, positron emission tomography–computed tomography | |
650 | 4 | |a WBC, white blood cells | |
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