Primary Liver Sinusoidal Non-Hodgkin's Lymphoma Presenting as Acute Liver Failure

We describe a case of a middle-aged woman, who presented to us with fever, anorexia, abdominal distension from a massive hepatomegaly, low hemoglobin, and acute liver failure. A liver biopsy revealed B cell non-Hodgkin's lymphoma predominantly in the sinusoids with CD10, CD20, and Bcl-2 positive on immunohistochemistry. She initially responded well to chemotherapy but succumbed 6 months later to the recurrence of disease. Sinusoidal non-Hodgkin's lymphoma of the liver should be considered in the differential diagnosis of a patient with large hepatomegaly presenting with acute liver failure.

Medienart:

E-Artikel

Erscheinungsjahr:

2015

Erschienen:

2015

Enthalten in:

Zur Gesamtaufnahme - volume:5

Enthalten in:

Journal of clinical and experimental hepatology - 5(2015), 4 vom: 28. Dez., Seite 341-3

Sprache:

Englisch

Beteiligte Personen:

Nagral, Aabha [VerfasserIn]
Jhaveri, Ajay [VerfasserIn]
Kalthoonical, Vilesh [VerfasserIn]
Bhat, Ganapathi [VerfasserIn]
Mahajan, Pravin [VerfasserIn]
Borges, Anita [VerfasserIn]

Links:

Volltext

Themen:

AFP, alpha feto protein
ALT, alanine aminotransferase
AST, aspartate aminotransferase
B cell
Bcl 2, B cell lymphoma 2
CD, cluster differentiation
CECT, contrast enhanced computed tomography
CHOP, cyclophosphamide hydroxydaunorubicin (adriyamycin) oncovin (vincristine) prednisolone
CK, cyto keratin
Chemotherapy
HBsAg, hepatitis B surface antigen
HCV, hepatitis C virus
HIV, human immunodeficiency virus
Hepatocyte
IgM, immunoglobulin M
Journal Article
Liver failure
NHL, non-Hodgkins lymphoma
PET CT, positron emission tomography–computed tomography
WBC, white blood cells

Anmerkungen:

Date Completed 22.02.2016

Date Revised 30.09.2020

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1016/j.jceh.2015.10.007

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM257700668