Evaluation of Ziehl-Neelsen smear for diagnosis of pulmonary tuberculosis in childhood in a rural hospital in Ethiopia

Copyright © 2013 Asian-African Society for Mycobacteriology. All rights reserved..

The goal of this study is to describe the experience with smear microscopy examination for acid-fast bacilli (AFB) of spontaneous sputum from children in a district hospital located in a rural zone of Ethiopia. All sputum reports of children were retrospectively reviewed from July 2007 until June 2012. During the period of study, 875 children less than 15years old were screened and 48 (5.5%, 95% confidence interval [CI]: 4.1-7.3%) were diagnosed with pulmonary tuberculosis sputum smear positive. The mean age of the children with sputum positive for AFB was significantly higher than children with sputum negative for AFB (11.4 versus 10.4) (p=0.001). Only 1 out of 47 (1.3%) children of 6years or less had sputum positive for AFB. In 13- and 14-year-old children, 8.7% had sputum positive for AFB (20 of 229) (p=0.03). Spontaneous sputum has a low diagnostic yield in childhood in low-income countries. Alternative methods should be implemented in rural areas to improve diagnosis of pulmonary TB, particularly in children less than 12years old.

Medienart:

E-Artikel

Erscheinungsjahr:

2013

Erschienen:

2013

Enthalten in:

Zur Gesamtaufnahme - volume:2

Enthalten in:

International journal of mycobacteriology - 2(2013), 3 vom: 19. Sept., Seite 171-3

Sprache:

Englisch

Beteiligte Personen:

Ramos, José Manuel [VerfasserIn]
Pérez-Butragueño, Mario [VerfasserIn]
Tisiano, Gabriel [VerfasserIn]
Yohannes, Tafese [VerfasserIn]
Reyes, Francisco [VerfasserIn]
Górgolas, Miguel [VerfasserIn]

Links:

Volltext

Themen:

Childhood
Journal Article
Paediatric tuberculosis
Smear
Sputum
Tuberculosis

Anmerkungen:

Date Completed 21.01.2016

Date Revised 20.01.2016

published: Print-Electronic

Citation Status PubMed-not-MEDLINE

doi:

10.1016/j.ijmyco.2013.04.007

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM256619174