α-Glucosidase and 15-Lipoxygenase Inhibitory Activities of Phytochemicals from Calophyllum symingtonianum
A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone, isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a positive result against 15-lipoxygenase inhibition.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Natural product communications - 10(2015), 9 vom: 19. Sept., Seite 1585-7 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Aminudin, Nurul Iman [VerfasserIn] |
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| Themen: |
Alpha-Glucosidases |
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| Anmerkungen: |
Date Completed 14.01.2016 Date Revised 23.11.2015 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM254881955 |
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| 100 | 1 | |a Aminudin, Nurul Iman |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a α-Glucosidase and 15-Lipoxygenase Inhibitory Activities of Phytochemicals from Calophyllum symingtonianum |
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| 500 | |a Date Revised 23.11.2015 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a A phytochemical investigation of the crude extracts of the bark and leaves of Calophyllum symingtonianum has resulted in the isolation of inophyllum D, inophyllum H, calanone, isocordato-oblongic acid, amentoflavone, carpachromene and lupenone. Their chemical structures were elucidated and confirmed by spectroscopic analysis. All flavonoids and coumarins showed significant α-glucosidase inhibitory activity, while amentoflavone gave a positive result against 15-lipoxygenase inhibition | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Glycoside Hydrolase Inhibitors |2 NLM | |
| 650 | 7 | |a Lipoxygenase Inhibitors |2 NLM | |
| 650 | 7 | |a Phytochemicals |2 NLM | |
| 650 | 7 | |a Arachidonate 15-Lipoxygenase |2 NLM | |
| 650 | 7 | |a EC 1.13.11.33 |2 NLM | |
| 650 | 7 | |a alpha-Glucosidases |2 NLM | |
| 650 | 7 | |a EC 3.2.1.20 |2 NLM | |
| 700 | 1 | |a Ahmad, Farediah |e verfasserin |4 aut | |
| 700 | 1 | |a Taher, Muhammad |e verfasserin |4 aut | |
| 700 | 1 | |a Zulkifli, Razauden Mohamed |e verfasserin |4 aut | |
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