Regulation of Eye Development by Protein Serine/Threonine Phosphatases-1 and -2A
The protein serine/threonine phosphatases-1 and -2A are major cellular phosphatases, playing a fundamental role in organisms from prokaryotes to eukaryotes. They contribute to 90% dephosphorylation in eukaryote proteins. In the eye, both phosphatases are highly expressed and display important functions in regulating normal eye development. Moreover, they are implicated in pathogenesis through modulation of stress-induced apoptosis. Here we review the recent progresses on these aspects.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
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| Enthalten in: |
Current molecular medicine - 15(2015), 10 vom: 23., Seite 944-51 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wang, L [VerfasserIn] |
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| Anmerkungen: |
Date Completed 08.09.2016 Date Revised 23.09.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM254856918 |
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| 520 | |a The protein serine/threonine phosphatases-1 and -2A are major cellular phosphatases, playing a fundamental role in organisms from prokaryotes to eukaryotes. They contribute to 90% dephosphorylation in eukaryote proteins. In the eye, both phosphatases are highly expressed and display important functions in regulating normal eye development. Moreover, they are implicated in pathogenesis through modulation of stress-induced apoptosis. Here we review the recent progresses on these aspects | ||
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| 700 | 1 | |a Huang, Z-X |e verfasserin |4 aut | |
| 700 | 1 | |a Nie, Q |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Z-F |e verfasserin |4 aut | |
| 700 | 1 | |a Ji, W-K |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, X-H |e verfasserin |4 aut | |
| 700 | 1 | |a Hu, W-F |e verfasserin |4 aut | |
| 700 | 1 | |a Gong, L-L |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, L |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, S |e verfasserin |4 aut | |
| 700 | 1 | |a Qi, R-L |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, T-H |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Z-G |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, W-B |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Y-Z |e verfasserin |4 aut | |
| 700 | 1 | |a Li, D W-C |e verfasserin |4 aut | |
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