Preliminary results from the French study on prenatal repair for fetal myelomeningoceles (the PRIUM study)
Copyright © 2015 Elsevier Masson SAS. All rights reserved..
OBJECTIVES: To present the preliminary results of the PRIUM study, a French pilot study of prenatal repair for myelomeningoceles (MMC).
MATERIAL AND METHODS: The fetal surgery for MMC is offered in cases of patients that did not opt for termination of pregnancy.
RESULTS: Thirty-six patients were referred in an 18-month period. Eight patients were not eligible for prenatal repair. Another type of dysraphism was made in 6 cases (one spina-lipoma, 5 cases of limited dorsal myeloschisis). Twenty-two patients were eligible to fetal surgery. A prenatal repair was performed in three cases (14%). Four patients opted for a conventional postnatal treatment. Fifteen patients opted for termination of the pregnancy.
CONCLUSION: The establishment of a prenatal repair of MMC protocol in France was justified. The experience of the first 18months of this study however suggests that only a limited number of couples will choose this procedure after specialized counseling in a reference center.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2016 |
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| Erschienen: |
2016 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:45 |
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| Enthalten in: |
Journal de gynecologie, obstetrique et biologie de la reproduction - 45(2016), 7 vom: 22. Sept., Seite 738-44 |
| Sprache: |
Französisch |
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| Weiterer Titel: |
Résultats préliminaires de l'étude PRIUM : programme de réparation in utero des myéloméningocèles |
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| Beteiligte Personen: |
Friszer, S [VerfasserIn] |
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| Links: |
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| Themen: |
Chirurgie fœtale |
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| Anmerkungen: |
Date Completed 17.04.2017 Date Revised 17.04.2017 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jgyn.2015.09.002 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM254614736 |
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| 245 | 1 | 0 | |a Preliminary results from the French study on prenatal repair for fetal myelomeningoceles (the PRIUM study) |
| 246 | 3 | 3 | |a Résultats préliminaires de l'étude PRIUM : programme de réparation in utero des myéloméningocèles |
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| 500 | |a Date Revised 17.04.2017 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2015 Elsevier Masson SAS. All rights reserved. | ||
| 520 | |a OBJECTIVES: To present the preliminary results of the PRIUM study, a French pilot study of prenatal repair for myelomeningoceles (MMC) | ||
| 520 | |a MATERIAL AND METHODS: The fetal surgery for MMC is offered in cases of patients that did not opt for termination of pregnancy | ||
| 520 | |a RESULTS: Thirty-six patients were referred in an 18-month period. Eight patients were not eligible for prenatal repair. Another type of dysraphism was made in 6 cases (one spina-lipoma, 5 cases of limited dorsal myeloschisis). Twenty-two patients were eligible to fetal surgery. A prenatal repair was performed in three cases (14%). Four patients opted for a conventional postnatal treatment. Fifteen patients opted for termination of the pregnancy | ||
| 520 | |a CONCLUSION: The establishment of a prenatal repair of MMC protocol in France was justified. The experience of the first 18months of this study however suggests that only a limited number of couples will choose this procedure after specialized counseling in a reference center | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Chirurgie fœtale | |
| 650 | 4 | |a Diagnostic prénatal | |
| 650 | 4 | |a Fetal surgery | |
| 650 | 4 | |a Myelomeningocele | |
| 650 | 4 | |a Myéloméningocèle | |
| 650 | 4 | |a Prenatal diagnosis | |
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| 700 | 1 | |a Di Rocco, F |e verfasserin |4 aut | |
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| 700 | 1 | |a Garel, C |e verfasserin |4 aut | |
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