Bacterial infection after orthotopic liver transplantation
INTRODUCTION: The authors reviewed the prevalence of postoperative infections, the results of bacterium cultures, and the incidence of multidrug resistance in their liver transplanted patients during a period between 2003 and 2012.
AIM: The aim of this study was to analyse risk factors and colonisations of bacterial infections.
METHOD: The files of 408 patients (281 bacterium cultures) were reviewed.
RESULTS: Of the 408 patients 70 had a postoperative infection (17%); 58 patients (14.2%) had positive and 12 patients (2.9%) negative bacterial culture results. Cholangitis was found in 7 cases (12.1%), abdominal infection in 17 cases (29.3%), and pulmonary infection in 28 cases (48.3%). Postoperative infection was more frequent in patients with initial poor graft function, acute renal insufficiency, biliary complication, and in those with intraabdominal bleeding. The 1-, 3- and 5-year cumulative survival of patients who had infection was 70%, 56% and 56%, respectively, whereas the cumulative survival data of patients without infection was 94%, 87% and 85%, respectively (p<0.001). Multidrug resistance was found in 56% of the positive cultures, however, the one-year survival was not different in patients who had multidrug resistance positive and negative bacterial infection (both 70.2%).
CONCLUSIONS: Infection control must target the management of multidrug resistance microbes through encouraging prevention, hygienic, and isolation rules, improving the operative, transfusion, and antimicrobial policy in a teamwork setting.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2015 |
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Erschienen: |
2015 |
Enthalten in: |
Zur Gesamtaufnahme - volume:156 |
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Enthalten in: |
Orvosi hetilap - 156(2015), 34 vom: 23. Aug., Seite 1366-82 |
Sprache: |
Ungarisch |
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Weiterer Titel: |
Bakteriális infekciók májátültetés után |
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Beteiligte Personen: |
Nemes, Balázs [VerfasserIn] |
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Links: |
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Themen: |
Bacterial infection |
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Anmerkungen: |
Date Completed 16.12.2015 Date Revised 17.08.2015 published: Print Citation Status MEDLINE |
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doi: |
10.1556/650.2015.30204 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM251882780 |
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520 | |a INTRODUCTION: The authors reviewed the prevalence of postoperative infections, the results of bacterium cultures, and the incidence of multidrug resistance in their liver transplanted patients during a period between 2003 and 2012 | ||
520 | |a AIM: The aim of this study was to analyse risk factors and colonisations of bacterial infections | ||
520 | |a METHOD: The files of 408 patients (281 bacterium cultures) were reviewed | ||
520 | |a RESULTS: Of the 408 patients 70 had a postoperative infection (17%); 58 patients (14.2%) had positive and 12 patients (2.9%) negative bacterial culture results. Cholangitis was found in 7 cases (12.1%), abdominal infection in 17 cases (29.3%), and pulmonary infection in 28 cases (48.3%). Postoperative infection was more frequent in patients with initial poor graft function, acute renal insufficiency, biliary complication, and in those with intraabdominal bleeding. The 1-, 3- and 5-year cumulative survival of patients who had infection was 70%, 56% and 56%, respectively, whereas the cumulative survival data of patients without infection was 94%, 87% and 85%, respectively (p<0.001). Multidrug resistance was found in 56% of the positive cultures, however, the one-year survival was not different in patients who had multidrug resistance positive and negative bacterial infection (both 70.2%) | ||
520 | |a CONCLUSIONS: Infection control must target the management of multidrug resistance microbes through encouraging prevention, hygienic, and isolation rules, improving the operative, transfusion, and antimicrobial policy in a teamwork setting | ||
650 | 4 | |a English Abstract | |
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700 | 1 | |a Kóbori, László |e verfasserin |4 aut | |
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