Trazodone in the elderly : risk of extrapyramidal acute events
2015 BMJ Publishing Group Ltd..
Trazodone is a second-generation atypical antidepressant exercising selective inhibitory action on the transport of serotonin. It also has an antagonist effect, similar to nefazodone, on the 5HT1 and 5HT2 receptors, probably due to the therapeutic effects of such substances. It is very effective in the treatment of depression, in anxiety and insomnia. Its known side effects mainly occur with prolonged use of daily doses of 150-200 mg. The ability to enhance drowsiness may be associated with some risk in elderly patients. This clinical case illustrates an acute extrapyramidal event induced by a low dose of trazodone.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2015 |
---|---|
Erschienen: |
2015 |
Enthalten in: |
Zur Gesamtaufnahme - volume:2015 |
---|---|
Enthalten in: |
BMJ case reports - 2015(2015) vom: 14. Juli |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Sotto Mayor, Joana [VerfasserIn] |
---|
Links: |
---|
Themen: |
Anti-Anxiety Agents |
---|
Anmerkungen: |
Date Completed 04.04.2016 Date Revised 07.12.2022 published: Electronic Citation Status MEDLINE |
---|
doi: |
10.1136/bcr-2015-210726 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM250883201 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM250883201 | ||
003 | DE-627 | ||
005 | 20231224160803.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231224s2015 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1136/bcr-2015-210726 |2 doi | |
028 | 5 | 2 | |a pubmed24n0836.xml |
035 | |a (DE-627)NLM250883201 | ||
035 | |a (NLM)26174731 | ||
035 | |a (PII)bcr2015210726 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Sotto Mayor, Joana |e verfasserin |4 aut | |
245 | 1 | 0 | |a Trazodone in the elderly |b risk of extrapyramidal acute events |
264 | 1 | |c 2015 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 04.04.2016 | ||
500 | |a Date Revised 07.12.2022 | ||
500 | |a published: Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a 2015 BMJ Publishing Group Ltd. | ||
520 | |a Trazodone is a second-generation atypical antidepressant exercising selective inhibitory action on the transport of serotonin. It also has an antagonist effect, similar to nefazodone, on the 5HT1 and 5HT2 receptors, probably due to the therapeutic effects of such substances. It is very effective in the treatment of depression, in anxiety and insomnia. Its known side effects mainly occur with prolonged use of daily doses of 150-200 mg. The ability to enhance drowsiness may be associated with some risk in elderly patients. This clinical case illustrates an acute extrapyramidal event induced by a low dose of trazodone | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a Journal Article | |
650 | 7 | |a Anti-Anxiety Agents |2 NLM | |
650 | 7 | |a Antidepressive Agents, Second-Generation |2 NLM | |
650 | 7 | |a Serotonin Uptake Inhibitors |2 NLM | |
650 | 7 | |a Trazodone |2 NLM | |
650 | 7 | |a YBK48BXK30 |2 NLM | |
700 | 1 | |a Pacheco, Ana Paula |e verfasserin |4 aut | |
700 | 1 | |a Esperança, Sofia |e verfasserin |4 aut | |
700 | 1 | |a Oliveira e Silva, Antonio |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t BMJ case reports |d 2008 |g 2015(2015) vom: 14. Juli |w (DE-627)NLM209291001 |x 1757-790X |7 nnns |
773 | 1 | 8 | |g volume:2015 |g year:2015 |g day:14 |g month:07 |
856 | 4 | 0 | |u http://dx.doi.org/10.1136/bcr-2015-210726 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 2015 |j 2015 |b 14 |c 07 |