Prospective study of depression among dialysis patients in Saudi Arabia

OBJECTIVES: The purpose was to determine the short-term course of depression among dialysis patients in Saudi Arabia and identify baseline characteristics that may influence course.

METHODS: Thirty-nine dialysis patients in Jeddah, SA, were identified with subthreshold, minor, or major depressive disorders using the Structured Clinical Interview for Depression (SCID) and followed up at 6 and 12 weeks using the Longitudinal Interview and Follow-up Evaluation (LIFE) schedule. Depressive symptoms were tracked using the Hamilton Depression Rating Scale (HDRS). Patient characteristics measured at baseline included demographic, psychosocial, physical health, and treatment factors.

RESULTS: Of the 20 patients with major or minor depressive disorder, eight (40 %) fully remitted by 6 weeks and an additional three patients remitted over the next 6 weeks, leaving 45 % with significant depressive symptoms persisting beyond 12 weeks. Subthreshold disorders followed a similar course (42 % with persistent symptoms). Few patients received treatment for depression. Those with more education, severe health problems, poorer psychological function, more severe depressive symptoms, or a family psychiatric history were less likely to remit. Similar factors predicted change in depressive symptoms assessed by HDRS, especially high medical co-morbidity, severe illness, and overall poor psychological functioning.

CONCLUSIONS: Nearly one-half of depressed dialysis patients in Saudi Arabia continue to have significant symptoms beyond 12 weeks of follow-up, few of whom were treated. Specific characteristics at baseline identify depressed dialysis patients at greater risk of persistent symptoms who need treatment.

Medienart:

E-Artikel

Erscheinungsjahr:

2015

Erschienen:

2015

Enthalten in:

Zur Gesamtaufnahme - volume:47

Enthalten in:

International urology and nephrology - 47(2015), 6 vom: 21. Juni, Seite 1001-10

Sprache:

Englisch

Beteiligte Personen:

Al Zaben, Faten [VerfasserIn]
Sehlo, Mohammad Gamal [VerfasserIn]
Khalifa, Doaa Ahmed [VerfasserIn]
Al Shohaib, Saad [VerfasserIn]
Shaheen, Faisul [VerfasserIn]
Alzaben, Linda [VerfasserIn]
Ahmad, Rami Ghazi [VerfasserIn]
Ashy, Jafar Ayman [VerfasserIn]
Felemban, Reema Ghazi [VerfasserIn]
Koenig, Harold G [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 25.02.2016

Date Revised 13.11.2018

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1007/s11255-015-0977-1

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM24830335X