IgG4-related disease is a rare differential diagnosis of malignant and autoimmune diseases
Immunoglobulin G4-related disease (IgG4-RD) is an inflammatory and fibrotic disease with the potential to produce diffuse enlargement, massforming lesions or stenoses in a wide range of organs. Elevation of serum IgG4 concentration and high levels of IgG4-positive cells in the inflamed tissue are common denominators. Type 1 autoimmune pancreatitis is one of the main manifestations, and its recognition preceded the definition of IgG4-RD as a novel clinical entity. The aetiology, pathophysiology, epidemiology and clinical long-term outcome of IgG4-RD are not fully elucidated. Steroids are effective in most patients, sometimes combined with other antiinflammatory drugs.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:177 |
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| Enthalten in: |
Ugeskrift for laeger - 177(2015), 15 vom: 06. Apr., Seite V09140507 |
| Sprache: |
Dänisch |
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| Weiterer Titel: |
Immunglobulin G4-relateret sygdom er en sjælden differentialdiagnose til maligne og autoimmune sygdomme |
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| Beteiligte Personen: |
Storgaard, Anders [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 30.01.2017 Date Revised 30.01.2017 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM248039091 |
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| 245 | 1 | 0 | |a IgG4-related disease is a rare differential diagnosis of malignant and autoimmune diseases |
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| 520 | |a Immunoglobulin G4-related disease (IgG4-RD) is an inflammatory and fibrotic disease with the potential to produce diffuse enlargement, massforming lesions or stenoses in a wide range of organs. Elevation of serum IgG4 concentration and high levels of IgG4-positive cells in the inflamed tissue are common denominators. Type 1 autoimmune pancreatitis is one of the main manifestations, and its recognition preceded the definition of IgG4-RD as a novel clinical entity. The aetiology, pathophysiology, epidemiology and clinical long-term outcome of IgG4-RD are not fully elucidated. Steroids are effective in most patients, sometimes combined with other antiinflammatory drugs | ||
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