Recurrent implantation failure and thrombophilia
OBJECTIVE: Bring a comprehensive overview of the available knowledge about the importance of thrombophilic mutations in patients with recurrent implantation failure and summary of therapeutic options.
DESIGN: Overview study.
SETTING: Department of Obstetric and Gynecology, University Hospital Olomouc.
METHODS: Analysis of literary sources and databases Ovid, Medline.
CONCLUSION: Failure of implantation in the context of assisted reproduction is associated with impaired endometrial receptivity. In women with normal anatomy may affect the implantation of embryos during stimulation hormonal changes, immunological factors or thrombophilic mutations. Recurrent implantation failure patients should be tested for the presence of thrombophilic mutations. Subsequently, these patients should be individually consulted and low molecular weight heparin should be used only in indicated cases. According to the available data treatment is recommended only in patients with known acquired or inherited thrombophilic disorder.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2015 |
|---|---|
| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:80 |
|---|---|
| Enthalten in: |
Ceska gynekologie - 80(2015), 1 vom: 18. Jan., Seite 5-10 |
| Sprache: |
Tschechisch |
|---|
| Weiterer Titel: |
Opakované selhání implantace embrya a trombofilie |
|---|
| Beteiligte Personen: |
Lattová, V [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 16.10.2015 Date Revised 02.12.2018 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM246618167 |
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| 100 | 1 | |a Lattová, V |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Recurrent implantation failure and thrombophilia |
| 246 | 3 | 3 | |a Opakované selhání implantace embrya a trombofilie |
| 264 | 1 | |c 2015 | |
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| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
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| 500 | |a Date Completed 16.10.2015 | ||
| 500 | |a Date Revised 02.12.2018 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: Bring a comprehensive overview of the available knowledge about the importance of thrombophilic mutations in patients with recurrent implantation failure and summary of therapeutic options | ||
| 520 | |a DESIGN: Overview study | ||
| 520 | |a SETTING: Department of Obstetric and Gynecology, University Hospital Olomouc | ||
| 520 | |a METHODS: Analysis of literary sources and databases Ovid, Medline | ||
| 520 | |a CONCLUSION: Failure of implantation in the context of assisted reproduction is associated with impaired endometrial receptivity. In women with normal anatomy may affect the implantation of embryos during stimulation hormonal changes, immunological factors or thrombophilic mutations. Recurrent implantation failure patients should be tested for the presence of thrombophilic mutations. Subsequently, these patients should be individually consulted and low molecular weight heparin should be used only in indicated cases. According to the available data treatment is recommended only in patients with known acquired or inherited thrombophilic disorder | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Pešková, M |e verfasserin |4 aut | |
| 700 | 1 | |a Sobek, A |c Jr |e verfasserin |4 aut | |
| 700 | 1 | |a Procházka, M |e verfasserin |4 aut | |
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