Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza : A Case Series From 8 Countries
Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US..
BACKGROUND: Data on causes of death due to respiratory illness in Africa are limited.
METHODS: From January to April 2013, 28 African countries were invited to participate in a review of severe acute respiratory illness (SARI)-associated deaths identified from influenza surveillance during 2009-2012.
RESULTS: Twenty-three countries (82%) responded, 11 (48%) collect mortality data, and 8 provided data. Data were collected from 37 714 SARI cases, and 3091 (8.2%; range by country, 5.1%-25.9%) tested positive for influenza virus. There were 1073 deaths (2.8%; range by country, 0.1%-5.3%) reported, among which influenza virus was detected in 57 (5.3%). Case-fatality proportion (CFP) was higher among countries with systematic death reporting than among those with sporadic reporting. The influenza-associated CFP was 1.8% (57 of 3091), compared with 2.9% (1016 of 34 623) for influenza virus-negative cases (P < .001). Among 834 deaths (77.7%) tested for other respiratory pathogens, rhinovirus (107 [12.8%]), adenovirus (64 [6.0%]), respiratory syncytial virus (60 [5.6%]), and Streptococcus pneumoniae (57 [5.3%]) were most commonly identified. Among 1073 deaths, 402 (37.5%) involved people aged 0-4 years, 462 (43.1%) involved people aged 5-49 years, and 209 (19.5%) involved people aged ≥50 years.
CONCLUSIONS: Few African countries systematically collect data on outcomes of people hospitalized with respiratory illness. Stronger surveillance for deaths due to respiratory illness may identify risk groups for targeted vaccine use and other prevention strategies.
| Errataetall: |
CommentIn: J Infect Dis. 2015 Sep 15;212(6):843-4. - PMID 25712971 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:212 |
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| Enthalten in: |
The Journal of infectious diseases - 212(2015), 6 vom: 15. Sept., Seite 853-60 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
McMorrow, Meredith L [VerfasserIn] |
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| Links: |
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| Themen: |
Africa South of the Sahara |
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| Anmerkungen: |
Date Completed 12.11.2015 Date Revised 13.11.2018 published: Print-Electronic CommentIn: J Infect Dis. 2015 Sep 15;212(6):843-4. - PMID 25712971 Citation Status MEDLINE |
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| doi: |
10.1093/infdis/jiv100 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 100 | 1 | |a McMorrow, Meredith L |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Severe Acute Respiratory Illness Deaths in Sub-Saharan Africa and the Role of Influenza |b A Case Series From 8 Countries |
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| 500 | |a Date Completed 12.11.2015 | ||
| 500 | |a Date Revised 13.11.2018 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a CommentIn: J Infect Dis. 2015 Sep 15;212(6):843-4. - PMID 25712971 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US. | ||
| 520 | |a BACKGROUND: Data on causes of death due to respiratory illness in Africa are limited | ||
| 520 | |a METHODS: From January to April 2013, 28 African countries were invited to participate in a review of severe acute respiratory illness (SARI)-associated deaths identified from influenza surveillance during 2009-2012 | ||
| 520 | |a RESULTS: Twenty-three countries (82%) responded, 11 (48%) collect mortality data, and 8 provided data. Data were collected from 37 714 SARI cases, and 3091 (8.2%; range by country, 5.1%-25.9%) tested positive for influenza virus. There were 1073 deaths (2.8%; range by country, 0.1%-5.3%) reported, among which influenza virus was detected in 57 (5.3%). Case-fatality proportion (CFP) was higher among countries with systematic death reporting than among those with sporadic reporting. The influenza-associated CFP was 1.8% (57 of 3091), compared with 2.9% (1016 of 34 623) for influenza virus-negative cases (P < .001). Among 834 deaths (77.7%) tested for other respiratory pathogens, rhinovirus (107 [12.8%]), adenovirus (64 [6.0%]), respiratory syncytial virus (60 [5.6%]), and Streptococcus pneumoniae (57 [5.3%]) were most commonly identified. Among 1073 deaths, 402 (37.5%) involved people aged 0-4 years, 462 (43.1%) involved people aged 5-49 years, and 209 (19.5%) involved people aged ≥50 years | ||
| 520 | |a CONCLUSIONS: Few African countries systematically collect data on outcomes of people hospitalized with respiratory illness. Stronger surveillance for deaths due to respiratory illness may identify risk groups for targeted vaccine use and other prevention strategies | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Research Support, U.S. Gov't, P.H.S. | |
| 650 | 4 | |a Africa South of the Sahara | |
| 650 | 4 | |a influenza, human | |
| 650 | 4 | |a mortality | |
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| 700 | 1 | |a Tshilobo, Joelle Kabamba |e verfasserin |4 aut | |
| 700 | 1 | |a Emukule, Gideon O |e verfasserin |4 aut | |
| 700 | 1 | |a Mott, Joshua A |e verfasserin |4 aut | |
| 700 | 1 | |a Njuguna, Henry |e verfasserin |4 aut | |
| 700 | 1 | |a Waiboci, Lilian |e verfasserin |4 aut | |
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