Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
BACKGROUND: The Antarctic moss Sanionia uncinata (Hedw.) Loeske has shown high ultraviolet (UV)-absorbers content after exposition to high levels of UV-B radiation and can be an important source of antioxidants.
OBJECTIVE: The aim was to investigate photoprotection and mutagenicity by the aqueous extract (AE) and hydroethanolic extract (HE) from the Antarctic moss S. uncinata.
MATERIALS AND METHODS: Photoprotective activities were determined through survival curves of Escherichia coli strains, after UV irradiation in an aqueous solution of thymine and in vitro sun protection factor (SPF). The Salmonella/microsome assays were applied to assess the mutagenicity.
RESULTS: Both extracts induced photoprotection against UV-C radiation. The AE showed a higher protection than the hydroethanolic one against UV-induced thymine dimerization. The SPFs were low in both extracts. In association to benzophenone-3 a significant increase in the SPF was detected for the AE, and a significant decrease was induced by the HE. No mutagenicity was found in the both extracts. Furthermore, it was observed absence of cytotoxicity.
CONCLUSION: Water-extractable compounds seem to contribute on photoprotection of this Antarctic moss.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
Pharmacognosy magazine - 11(2015), 41 vom: 14. Jan., Seite 38-43 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Fernandes, Andréia da Silva [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 24.02.2015 Date Revised 01.10.2020 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.4103/0973-1296.149701 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM246501324 |
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| 100 | 1 | |a Fernandes, Andréia da Silva |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata |
| 264 | 1 | |c 2015 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
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| 500 | |a Date Completed 24.02.2015 | ||
| 500 | |a Date Revised 01.10.2020 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a BACKGROUND: The Antarctic moss Sanionia uncinata (Hedw.) Loeske has shown high ultraviolet (UV)-absorbers content after exposition to high levels of UV-B radiation and can be an important source of antioxidants | ||
| 520 | |a OBJECTIVE: The aim was to investigate photoprotection and mutagenicity by the aqueous extract (AE) and hydroethanolic extract (HE) from the Antarctic moss S. uncinata | ||
| 520 | |a MATERIALS AND METHODS: Photoprotective activities were determined through survival curves of Escherichia coli strains, after UV irradiation in an aqueous solution of thymine and in vitro sun protection factor (SPF). The Salmonella/microsome assays were applied to assess the mutagenicity | ||
| 520 | |a RESULTS: Both extracts induced photoprotection against UV-C radiation. The AE showed a higher protection than the hydroethanolic one against UV-induced thymine dimerization. The SPFs were low in both extracts. In association to benzophenone-3 a significant increase in the SPF was detected for the AE, and a significant decrease was induced by the HE. No mutagenicity was found in the both extracts. Furthermore, it was observed absence of cytotoxicity | ||
| 520 | |a CONCLUSION: Water-extractable compounds seem to contribute on photoprotection of this Antarctic moss | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Moss | |
| 650 | 4 | |a mutagenicity | |
| 650 | 4 | |a photoprotection | |
| 650 | 4 | |a sun protection factor | |
| 650 | 4 | |a thymine-dimer inhibition | |
| 700 | 1 | |a Alencar, Alexandre Santos |e verfasserin |4 aut | |
| 700 | 1 | |a Evangelista, Heitor |e verfasserin |4 aut | |
| 700 | 1 | |a Mazzei, José Luiz |e verfasserin |4 aut | |
| 700 | 1 | |a Felzenszwalb, Israel |e verfasserin |4 aut | |
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