Assessment of long-term cognitive impairment after off-pump coronary-artery bypass grafting and related risk factors
Copyright © 2015 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved..
OBJECTIVES: To assess cognitive impairment after off-pump coronary-artery bypass grafting, with a particular emphasis on long-term follow-up and related risk factors.
DESIGN: Prospective study.
SETTING: Virgen de la Victoria University Hospital, Málaga, Spain.
PARTICIPANTS: Participants were 36 patients undergoing off-pump coronary-artery bypass grafting.
MEASUREMENTS: Changes in the neuropsychological test battery administered from before to after surgery (1, 6, and 12 months). Postoperative cognitive impairment was defined by a significant decrease.
RESULTS: A significantly multidomain (attention-executive functions, P < .01; immediate and delayed memory, P < .001; and verbal fluency, P < .05) postoperative cognitive impairment was shown, being maximum at 6 months (more than 50% of patients) and still presented at 12 months (more than 30% of patients), but partially recovered. Related risk factors as smoking (P < .01), diabetes mellitus (P < .01), peripheral arteriopathy (P < .01), obesity (P < .05), lower hematocrit (P < .01), and hemoglobin (P < .05) levels and diastolic blood pressure (P < .05) were identified as predictors of cognitive impairment. Better New York Heart Association class (P < .01) and less severity of angina (P < .01) were associated with partial postoperative recovering.
CONCLUSION: A multidomain long-term postoperative cognitive impairment and a partial neurocognitive recovering were detected after off-pump coronary-artery bypass grafting and were associated with several nonspecific surgery factors. These findings may be useful when counseling patients before surgery and suggest the importance of long-term neurocognitive evaluation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:16 |
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| Enthalten in: |
Journal of the American Medical Directors Association - 16(2015), 3 vom: 04. März, Seite 263.e9-11 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Pérez-Belmonte, Luis M [VerfasserIn] |
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| Links: |
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| Themen: |
Cognitive domain |
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| Anmerkungen: |
Date Completed 25.04.2016 Date Revised 10.12.2019 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jamda.2014.12.001 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 100 | 1 | |a Pérez-Belmonte, Luis M |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Assessment of long-term cognitive impairment after off-pump coronary-artery bypass grafting and related risk factors |
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| 500 | |a Date Revised 10.12.2019 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2015 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved. | ||
| 520 | |a OBJECTIVES: To assess cognitive impairment after off-pump coronary-artery bypass grafting, with a particular emphasis on long-term follow-up and related risk factors | ||
| 520 | |a DESIGN: Prospective study | ||
| 520 | |a SETTING: Virgen de la Victoria University Hospital, Málaga, Spain | ||
| 520 | |a PARTICIPANTS: Participants were 36 patients undergoing off-pump coronary-artery bypass grafting | ||
| 520 | |a MEASUREMENTS: Changes in the neuropsychological test battery administered from before to after surgery (1, 6, and 12 months). Postoperative cognitive impairment was defined by a significant decrease | ||
| 520 | |a RESULTS: A significantly multidomain (attention-executive functions, P < .01; immediate and delayed memory, P < .001; and verbal fluency, P < .05) postoperative cognitive impairment was shown, being maximum at 6 months (more than 50% of patients) and still presented at 12 months (more than 30% of patients), but partially recovered. Related risk factors as smoking (P < .01), diabetes mellitus (P < .01), peripheral arteriopathy (P < .01), obesity (P < .05), lower hematocrit (P < .01), and hemoglobin (P < .05) levels and diastolic blood pressure (P < .05) were identified as predictors of cognitive impairment. Better New York Heart Association class (P < .01) and less severity of angina (P < .01) were associated with partial postoperative recovering | ||
| 520 | |a CONCLUSION: A multidomain long-term postoperative cognitive impairment and a partial neurocognitive recovering were detected after off-pump coronary-artery bypass grafting and were associated with several nonspecific surgery factors. These findings may be useful when counseling patients before surgery and suggest the importance of long-term neurocognitive evaluation | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Evaluation Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Postoperative cognitive impairment | |
| 650 | 4 | |a cognitive domain | |
| 650 | 4 | |a coronary-artery bypass grafting | |
| 650 | 4 | |a off-pump | |
| 650 | 4 | |a predictors of cognitive impairment | |
| 650 | 4 | |a risk factors | |
| 700 | 1 | |a San Román-Terán, Carlos M |e verfasserin |4 aut | |
| 700 | 1 | |a Jiménez-Navarro, Manuel |e verfasserin |4 aut | |
| 700 | 1 | |a Barbancho, Miguel A |e verfasserin |4 aut | |
| 700 | 1 | |a García-Alberca, José M |e verfasserin |4 aut | |
| 700 | 1 | |a Lara, José P |e verfasserin |4 aut | |
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