Synthesis of small-sized, porous, and low-toxic magnetite nanoparticles by thin POSS silica coating
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim..
In this communication, we report the synthesis of small-sized (<10 nm), water-soluble, magnetic nanoparticles (MNPs) coated with polyhedral oligomeric silsesquioxanes (POSS), which contain either polyethylene glycol (PEG) or octa(tetramethylammonium) (OctaTMA) as functional groups. The POSS-coated MNPs exhibit superparamagnetic behavior with saturation magnetic moments (51-53 emu g(-1)) comparable to silica-coated MNPs. They also provide good colloidal stability at different pH and salt concentrations, and low cytotoxicity to MCF-7 human breast epithelial cells. The relaxivity data and magnetic resonance (MR) phantom images demonstrate the potential application of these MNPs in bioimaging.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2015 |
|---|---|
| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
|---|---|
| Enthalten in: |
Chemistry (Weinheim an der Bergstrasse, Germany) - 21(2015), 10 vom: 02. März, Seite 3914-8 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Yen, Swee Kuan [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 05.11.2015 Date Revised 02.12.2018 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1002/chem.201406388 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM245747737 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM245747737 | ||
| 003 | DE-627 | ||
| 005 | 20231224141543.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/chem.201406388 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0819.xml |
| 035 | |a (DE-627)NLM245747737 | ||
| 035 | |a (NLM)25630810 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Yen, Swee Kuan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Synthesis of small-sized, porous, and low-toxic magnetite nanoparticles by thin POSS silica coating |
| 264 | 1 | |c 2015 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 05.11.2015 | ||
| 500 | |a Date Revised 02.12.2018 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | ||
| 520 | |a In this communication, we report the synthesis of small-sized (<10 nm), water-soluble, magnetic nanoparticles (MNPs) coated with polyhedral oligomeric silsesquioxanes (POSS), which contain either polyethylene glycol (PEG) or octa(tetramethylammonium) (OctaTMA) as functional groups. The POSS-coated MNPs exhibit superparamagnetic behavior with saturation magnetic moments (51-53 emu g(-1)) comparable to silica-coated MNPs. They also provide good colloidal stability at different pH and salt concentrations, and low cytotoxicity to MCF-7 human breast epithelial cells. The relaxivity data and magnetic resonance (MR) phantom images demonstrate the potential application of these MNPs in bioimaging | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a iron oxide | |
| 650 | 4 | |a ligand exchange | |
| 650 | 4 | |a magnetic properties | |
| 650 | 4 | |a magnetic resonance imaging | |
| 650 | 4 | |a nanoparticles | |
| 650 | 7 | |a Ferric Compounds |2 NLM | |
| 650 | 7 | |a Magnetite Nanoparticles |2 NLM | |
| 650 | 7 | |a Organosilicon Compounds |2 NLM | |
| 650 | 7 | |a Quaternary Ammonium Compounds |2 NLM | |
| 650 | 7 | |a Polyethylene Glycols |2 NLM | |
| 650 | 7 | |a 3WJQ0SDW1A |2 NLM | |
| 650 | 7 | |a Silicon Dioxide |2 NLM | |
| 650 | 7 | |a 7631-86-9 |2 NLM | |
| 650 | 7 | |a tetramethylammonium |2 NLM | |
| 650 | 7 | |a H0W55235FC |2 NLM | |
| 700 | 1 | |a Varma, D Prathyusha |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Wei Mei |e verfasserin |4 aut | |
| 700 | 1 | |a Ho, Vincent H B |e verfasserin |4 aut | |
| 700 | 1 | |a Vijayaragavan, Vimalan |e verfasserin |4 aut | |
| 700 | 1 | |a Padmanabhan, Parasuraman |e verfasserin |4 aut | |
| 700 | 1 | |a Bhakoo, Kishore |e verfasserin |4 aut | |
| 700 | 1 | |a Selvan, Subramanian Tamil |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Chemistry (Weinheim an der Bergstrasse, Germany) |d 1996 |g 21(2015), 10 vom: 02. März, Seite 3914-8 |w (DE-627)NLM09455398X |x 1521-3765 |7 nnns |
| 773 | 1 | 8 | |g volume:21 |g year:2015 |g number:10 |g day:02 |g month:03 |g pages:3914-8 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1002/chem.201406388 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 21 |j 2015 |e 10 |b 02 |c 03 |h 3914-8 | ||