Clinical relevance of rhinovirus infections among adult hospitalized patients
Copyright © 2014 Elsevier Editora Ltda. All rights reserved..
UNLABELLED: Human rhinovirus (HRV) is an emerging viral pathogen.
AIM: To characterize a group of patients admitted due to infection by this agent in a general hospital in Chile.
METHODS: Cases were identified by RT-PCR for 1 year through active surveillance of patients admitted with severe respiratory illness. Diagnosis was not available during hospitalization. Thirty-two cases were identified, 90% were ≥60 years old or had co-morbid conditions. Human rhinovirus-related admissions represented 23.7% of hospitalization due to severe acute respiratory infections among adults and ranked second to influenza (37.8%). Patients presented with pneumonia (68.8%), decompensated chronic lung conditions (21.9%), heart failure or influenza-like illness (6.3% each). Admission to intensive or intermediate care units was required by 31.2% and in-hospital mortality reached 12.5%. A CURB-65 score ≥3 was significantly associated to in-hospital mortality (p<0.05). Most patients received antibiotics (90%).
CONCLUSIONS: Human rhinovirus infections in elderly patients with co-morbid conditions are associated with hospitalizations, requiring critical or semi-critical antibiotics use. A high CURB-65 score was associated to in-hospital mortality.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2015 |
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| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
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| Enthalten in: |
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 19(2015), 2 vom: 19. März, Seite 118-24 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Fica, Alberto [VerfasserIn] |
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| Links: |
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| Themen: |
Adult |
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| Anmerkungen: |
Date Completed 13.01.2016 Date Revised 08.04.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.bjid.2014.10.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM244717591 |
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| 500 | |a Date Completed 13.01.2016 | ||
| 500 | |a Date Revised 08.04.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2014 Elsevier Editora Ltda. All rights reserved. | ||
| 520 | |a UNLABELLED: Human rhinovirus (HRV) is an emerging viral pathogen | ||
| 520 | |a AIM: To characterize a group of patients admitted due to infection by this agent in a general hospital in Chile | ||
| 520 | |a METHODS: Cases were identified by RT-PCR for 1 year through active surveillance of patients admitted with severe respiratory illness. Diagnosis was not available during hospitalization. Thirty-two cases were identified, 90% were ≥60 years old or had co-morbid conditions. Human rhinovirus-related admissions represented 23.7% of hospitalization due to severe acute respiratory infections among adults and ranked second to influenza (37.8%). Patients presented with pneumonia (68.8%), decompensated chronic lung conditions (21.9%), heart failure or influenza-like illness (6.3% each). Admission to intensive or intermediate care units was required by 31.2% and in-hospital mortality reached 12.5%. A CURB-65 score ≥3 was significantly associated to in-hospital mortality (p<0.05). Most patients received antibiotics (90%) | ||
| 520 | |a CONCLUSIONS: Human rhinovirus infections in elderly patients with co-morbid conditions are associated with hospitalizations, requiring critical or semi-critical antibiotics use. A high CURB-65 score was associated to in-hospital mortality | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Adult | |
| 650 | 4 | |a Hospitalization | |
| 650 | 4 | |a Respiratory tract infections | |
| 650 | 4 | |a Reverse transcriptase polymerase chain reaction | |
| 650 | 4 | |a Rhinovirus | |
| 650 | 4 | |a Viral pneumonia | |
| 700 | 1 | |a Dabanch, Jeannette |e verfasserin |4 aut | |
| 700 | 1 | |a Andrade, Winston |e verfasserin |4 aut | |
| 700 | 1 | |a Bustos, Patricia |e verfasserin |4 aut | |
| 700 | 1 | |a Carvajal, Ita |e verfasserin |4 aut | |
| 700 | 1 | |a Ceroni, Carolina |e verfasserin |4 aut | |
| 700 | 1 | |a Triantafilo, Vjera |e verfasserin |4 aut | |
| 700 | 1 | |a Castro, Marcelo |e verfasserin |4 aut | |
| 700 | 1 | |a Fasce, Rodrigo |e verfasserin |4 aut | |
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