In situ labelling chemistry of respiratory syncytial viruses by employing the biotinylated host-cell membrane protein for tracking the early stage of virus entry

An in situ labelling strategy was proposed to produce quantum dot-labelled respiratory syncytial viruses (RSVs) by incorporating the biotinylated membrane protein of the host cells into mature virions, followed by conjugation with streptavidin modified quantum dots (SA-QDs), which has the advantages such as convenience, efficiency and minor influence on viral infectivity and thus could be successfully applied to track the early stage of virus entry.

Medienart:

E-Artikel

Erscheinungsjahr:

2014

Erschienen:

2014

Enthalten in:

Zur Gesamtaufnahme - volume:50

Enthalten in:

Chemical communications (Cambridge, England) - 50(2014), 99 vom: 25. Dez., Seite 15776-9

Sprache:

Englisch

Beteiligte Personen:

Zheng, Lin Ling [VerfasserIn]
Yang, Xiao Xi [VerfasserIn]
Liu, Yue [VerfasserIn]
Wan, Xiao Yan [VerfasserIn]
Wu, Wen Bi [VerfasserIn]
Wang, Ting Ting [VerfasserIn]
Wang, Qiang [VerfasserIn]
Zhen, Shu Jun [VerfasserIn]
Huang, Cheng Zhi [VerfasserIn]

Links:

Volltext

Themen:

6SO6U10H04
9013-20-1
Biotin
Fluorescent Dyes
Journal Article
Membrane Proteins
RNA, Viral
Research Support, Non-U.S. Gov't
Streptavidin

Anmerkungen:

Date Completed 06.07.2015

Date Revised 21.11.2014

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1039/c4cc06264g

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM243291973