Combined use of Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses is a powerful diagnostic tool of active tuberculosis

© The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America..

Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection.

Medienart:

E-Artikel

Erscheinungsjahr:

2015

Erschienen:

2015

Enthalten in:

Zur Gesamtaufnahme - volume:60

Enthalten in:

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 60(2015), 3 vom: 01. Feb., Seite 432-7

Sprache:

Englisch

Beteiligte Personen:

Rozot, Virginie [VerfasserIn]
Patrizia, Amelio [VerfasserIn]
Vigano, Selena [VerfasserIn]
Mazza-Stalder, Jesica [VerfasserIn]
Idrizi, Elita [VerfasserIn]
Day, Cheryl L [VerfasserIn]
Perreau, Matthieu [VerfasserIn]
Lazor-Blanchet, Catherine [VerfasserIn]
Ohmiti, Khalid [VerfasserIn]
Goletti, Delia [VerfasserIn]
Bart, Pierre-Alexandre [VerfasserIn]
Hanekom, Willem [VerfasserIn]
Scriba, Thomas J [VerfasserIn]
Nicod, Laurent [VerfasserIn]
Pantaleo, Giuseppe [VerfasserIn]
Harari, Alexandre [VerfasserIn]

Links:

Volltext

Themen:

Active tuberculosis disease
Antigens, Bacterial
CD8 T cells
Diagnosis
Functional profile
Journal Article
Latent Mtb infection
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 11.09.2015

Date Revised 21.10.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1093/cid/ciu795

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM243212259