Feasibility and clinical utility of ultra-widefield indocyanine green angiography

PURPOSE: To evaluate the feasibility and clinical utility of a novel noncontact scanning laser ophthalmoscope-based ultra-widefield indocyanine green angiographic system.

METHODS: Ultra-widefield indocyanine green angiographic images were captured using a modified Optos P200Tx that produced high-resolution images of the choroidal vasculature with up to a 200° field. Ultra-widefield indocyanine green angiography was performed on patients with a variety of retinal conditions to assess utility of this imaging technique for diagnostic purposes and disease treatment monitoring.

RESULTS: Ultra-widefield indocyanine green angiography was performed on 138 eyes of 69 patients. Mean age was 58 ± 16.9 years (range, 24-85 years). The most common ocular pathologies imaged included central serous chorioretinopathy (24 eyes), uveitis (various subtypes, 16 eyes), age-related macular degeneration (12 eyes), and polypoidal choroidal vasculopathy (4 eyes). In all eyes evaluated with ultra-widefield indocyanine green angiography, high-resolution images of choroidal and retinal circulation were obtained with sufficient detail out to 200° of the fundus.

CONCLUSION: In this series of 138 eyes, scanning laser ophthalmoscope-based ultra-widefield indocyanine green angiography was clinically practical and provided detailed images of both the central and peripheral choroidal circulation. Future studies are needed to refine the clinical value of this imaging modality and the significance of peripheral choroidal vascular changes in the diagnosis, monitoring, and treatment of ocular diseases.

Medienart:

E-Artikel

Erscheinungsjahr:

2015

Erschienen:

2015

Enthalten in:

Zur Gesamtaufnahme - volume:35

Enthalten in:

Retina (Philadelphia, Pa.) - 35(2015), 3 vom: 09. März, Seite 508-20

Sprache:

Englisch

Beteiligte Personen:

Klufas, Michael A [VerfasserIn]
Yannuzzi, Nicolas A [VerfasserIn]
Pang, Claudine E [VerfasserIn]
Srinivas, Sowmya [VerfasserIn]
Sadda, Srinivas R [VerfasserIn]
Freund, K Bailey [VerfasserIn]
Kiss, Szilárd [VerfasserIn]

Links:

Volltext

Themen:

Coloring Agents
IX6J1063HV
Indocyanine Green
Journal Article
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 26.08.2015

Date Revised 19.11.2015

published: Print

Citation Status MEDLINE

doi:

10.1097/IAE.0000000000000318

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM242172075