Pre-clinical optical imaging and MRI for drug development in Alzheimer's disease
© 2011 Elsevier Ltd . All rights reserved..
Optical and magnetic resonance imaging have the potential to be complementary non-invasive imaging modalities. Yet without advances in imaging technologies and contrast agents both have short-comings that cannot be ignored. In this review we demonstrate the pre-clinical use of the two imaging techniques in Alzheimer's disease, including examples from recent applications and discuss what is needed to improve their applicability for drug discovery.:.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:8 |
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| Enthalten in: |
Drug discovery today. Technologies - 8(2011), 2-4 vom: 02., Seite e117-25 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rotman, Maarten [VerfasserIn] |
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| Anmerkungen: |
Date Completed 04.07.2014 Date Revised 03.07.2014 published: Print Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1016/j.ddtec.2011.11.005 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Optical and magnetic resonance imaging have the potential to be complementary non-invasive imaging modalities. Yet without advances in imaging technologies and contrast agents both have short-comings that cannot be ignored. In this review we demonstrate the pre-clinical use of the two imaging techniques in Alzheimer's disease, including examples from recent applications and discuss what is needed to improve their applicability for drug discovery.: | ||
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