Clinical and molecular study of 4 cases of pulmonary hypertension associated with sarcoidosis
Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved..
Sarcoidosis is a pleomorphic disease that can present with pulmonary hypertension (PH). What little information is available about the association of these two diseases comes mainly from small series of patients scheduled for transplant. We present 4 cases of mild pulmonary involvement in whom right catheterisation was performed and PH-specific therapy was administered. After obtaining written consent, a genetic study was performed that showed mutations in PH-related genes in 3 of the patients. This is the first study of its kind to yield genetic information for this type of PH.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2015 |
|---|---|
| Erschienen: |
2015 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:51 |
|---|---|
| Enthalten in: |
Archivos de bronconeumologia - 51(2015), 4 vom: 20. Apr., Seite e19-21 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Baloira Villar, Adolfo [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 21.12.2015 Date Revised 02.12.2018 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.arbres.2014.03.022 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM23938606X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM23938606X | ||
| 003 | DE-627 | ||
| 005 | 20231224115833.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2015 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.arbres.2014.03.022 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0798.xml |
| 035 | |a (DE-627)NLM23938606X | ||
| 035 | |a (NLM)24950668 | ||
| 035 | |a (PII)S0300-2896(14)00191-4 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Baloira Villar, Adolfo |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Clinical and molecular study of 4 cases of pulmonary hypertension associated with sarcoidosis |
| 264 | 1 | |c 2015 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 21.12.2015 | ||
| 500 | |a Date Revised 02.12.2018 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved. | ||
| 520 | |a Sarcoidosis is a pleomorphic disease that can present with pulmonary hypertension (PH). What little information is available about the association of these two diseases comes mainly from small series of patients scheduled for transplant. We present 4 cases of mild pulmonary involvement in whom right catheterisation was performed and PH-specific therapy was administered. After obtaining written consent, a genetic study was performed that showed mutations in PH-related genes in 3 of the patients. This is the first study of its kind to yield genetic information for this type of PH | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Hipertensión pulmonar | |
| 650 | 4 | |a Mutaciones | |
| 650 | 4 | |a Mutations | |
| 650 | 4 | |a Pulmonary hypertension | |
| 650 | 4 | |a Sarcoidosis | |
| 650 | 7 | |a KCNA5 protein, human |2 NLM | |
| 650 | 7 | |a Kv1.5 Potassium Channel |2 NLM | |
| 650 | 7 | |a Phenylpropionates |2 NLM | |
| 650 | 7 | |a Pyridazines |2 NLM | |
| 650 | 7 | |a RNA, Messenger |2 NLM | |
| 650 | 7 | |a Sulfonamides |2 NLM | |
| 650 | 7 | |a Tadalafil |2 NLM | |
| 650 | 7 | |a 742SXX0ICT |2 NLM | |
| 650 | 7 | |a Sildenafil Citrate |2 NLM | |
| 650 | 7 | |a BW9B0ZE037 |2 NLM | |
| 650 | 7 | |a Epoprostenol |2 NLM | |
| 650 | 7 | |a DCR9Z582X0 |2 NLM | |
| 650 | 7 | |a BMPR2 protein, human |2 NLM | |
| 650 | 7 | |a EC 2.7.11.30 |2 NLM | |
| 650 | 7 | |a Bone Morphogenetic Protein Receptors, Type II |2 NLM | |
| 650 | 7 | |a EC 2.7.11.30 |2 NLM | |
| 650 | 7 | |a ambrisentan |2 NLM | |
| 650 | 7 | |a HW6NV07QEC |2 NLM | |
| 650 | 7 | |a Bosentan |2 NLM | |
| 650 | 7 | |a Q326023R30 |2 NLM | |
| 650 | 7 | |a treprostinil |2 NLM | |
| 650 | 7 | |a RUM6K67ESG |2 NLM | |
| 700 | 1 | |a Pousada Fernández, Guillermo |e verfasserin |4 aut | |
| 700 | 1 | |a Núñez Fernández, Marta |e verfasserin |4 aut | |
| 700 | 1 | |a Valverde Pérez, Diana |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Archivos de bronconeumologia |d 1994 |g 51(2015), 4 vom: 20. Apr., Seite e19-21 |w (DE-627)NLM07558641X |x 1579-2129 |7 nnns |
| 773 | 1 | 8 | |g volume:51 |g year:2015 |g number:4 |g day:20 |g month:04 |g pages:e19-21 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.arbres.2014.03.022 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 51 |j 2015 |e 4 |b 20 |c 04 |h e19-21 | ||