A comparison of risk factors for mortality from heart failure in Asian and non-Asian populations : an overview of individual participant data from 32 prospective cohorts from the Asia-Pacific Region
BACKGROUND: Most of what is known regarding the epidemiology of mortality from heart failure (HF) comes from studies within Western populations with few data available from the Asia-Pacific region where the burden of heart failure is increasing.
METHODS: Individual level data from 543694 (85% Asian; 36% female) participants from 32 cohorts in the Asia Pacific Cohort Studies Collaboration were included in the analysis. Adjusted hazard ratios (HR) and 95% confidence intervals (CI) for mortality from HF were estimated separately for Asians and non-Asians for a quintet of cardiovascular risk factors: systolic blood pressure, diabetes, body mass index, cigarette smoking and total cholesterol. All analyses were stratified by sex and study.
RESULTS: During 3,793,229 person years of follow-up there were 614 HF deaths (80% Asian). The positive associations between elevated blood pressure, obesity, and cigarette smoking were consistent for Asians and non-Asians. There was evidence to indicate that diabetes was a weaker risk factor for death from HF for Asians compared with non-Asians: HR 1.26 (95% CI: 0.74-2.13) versus 3.04 (95% CI 1.76-5.25) respectively; p for interaction = 0.022. Additional adjustment for covariates did not materially change the overall associations. There was no good evidence to indicate that total cholesterol was a risk factor for HF mortality in either population.
CONCLUSIONS: Most traditional cardiovascular risk factors including elevated blood pressure, obesity and cigarette smoking appear to operate similarly to increase the risk of death from HF in Asians and non-Asians populations alike.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2014 |
|---|---|
| Erschienen: |
2014 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
|---|---|
| Enthalten in: |
BMC cardiovascular disorders - 14(2014) vom: 03. Mai, Seite 61 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Huxley, Rachel R [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Journal Article |
|---|
| Anmerkungen: |
Date Completed 20.01.2015 Date Revised 07.12.2022 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1186/1471-2261-14-61 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM238753425 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM238753425 | ||
| 003 | DE-627 | ||
| 005 | 20231224114453.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2014 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1186/1471-2261-14-61 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0795.xml |
| 035 | |a (DE-627)NLM238753425 | ||
| 035 | |a (NLM)24884382 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Huxley, Rachel R |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A comparison of risk factors for mortality from heart failure in Asian and non-Asian populations |b an overview of individual participant data from 32 prospective cohorts from the Asia-Pacific Region |
| 264 | 1 | |c 2014 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 20.01.2015 | ||
| 500 | |a Date Revised 07.12.2022 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Most of what is known regarding the epidemiology of mortality from heart failure (HF) comes from studies within Western populations with few data available from the Asia-Pacific region where the burden of heart failure is increasing | ||
| 520 | |a METHODS: Individual level data from 543694 (85% Asian; 36% female) participants from 32 cohorts in the Asia Pacific Cohort Studies Collaboration were included in the analysis. Adjusted hazard ratios (HR) and 95% confidence intervals (CI) for mortality from HF were estimated separately for Asians and non-Asians for a quintet of cardiovascular risk factors: systolic blood pressure, diabetes, body mass index, cigarette smoking and total cholesterol. All analyses were stratified by sex and study | ||
| 520 | |a RESULTS: During 3,793,229 person years of follow-up there were 614 HF deaths (80% Asian). The positive associations between elevated blood pressure, obesity, and cigarette smoking were consistent for Asians and non-Asians. There was evidence to indicate that diabetes was a weaker risk factor for death from HF for Asians compared with non-Asians: HR 1.26 (95% CI: 0.74-2.13) versus 3.04 (95% CI 1.76-5.25) respectively; p for interaction = 0.022. Additional adjustment for covariates did not materially change the overall associations. There was no good evidence to indicate that total cholesterol was a risk factor for HF mortality in either population | ||
| 520 | |a CONCLUSIONS: Most traditional cardiovascular risk factors including elevated blood pressure, obesity and cigarette smoking appear to operate similarly to increase the risk of death from HF in Asians and non-Asians populations alike | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Meta-Analysis | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 700 | 1 | |a Barzi, Federica |e verfasserin |4 aut | |
| 700 | 1 | |a Woo, Jean |e verfasserin |4 aut | |
| 700 | 1 | |a Giles, Graham |e verfasserin |4 aut | |
| 700 | 1 | |a Lam, Tai Hing |e verfasserin |4 aut | |
| 700 | 1 | |a Rahimi, Kazem |e verfasserin |4 aut | |
| 700 | 1 | |a Konety, Suma |e verfasserin |4 aut | |
| 700 | 1 | |a Ohkubo, Takayoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Jee, Sun Ha |e verfasserin |4 aut | |
| 700 | 1 | |a Fang, Xianghua |e verfasserin |4 aut | |
| 700 | 1 | |a Woodward, Mark |e verfasserin |4 aut | |
| 700 | 0 | |a Asia Pacific Cohort Studies Collaboration |e verfasserin |4 aut | |
| 700 | 1 | |a Woodward, M |e investigator |4 oth | |
| 700 | 1 | |a Fang, X |e investigator |4 oth | |
| 700 | 1 | |a Gu, D F |e investigator |4 oth | |
| 700 | 1 | |a Huxley, R |e investigator |4 oth | |
| 700 | 1 | |a Imai, Y |e investigator |4 oth | |
| 700 | 1 | |a Kim, H C |e investigator |4 oth | |
| 700 | 1 | |a Lam, T H |e investigator |4 oth | |
| 700 | 1 | |a Pan, W H |e investigator |4 oth | |
| 700 | 1 | |a Rodgers, A |e investigator |4 oth | |
| 700 | 1 | |a Suh, I |e investigator |4 oth | |
| 700 | 1 | |a Ueshima, H |e investigator |4 oth | |
| 700 | 1 | |a Okayama, A |e investigator |4 oth | |
| 700 | 1 | |a Ueshima, H |e investigator |4 oth | |
| 700 | 1 | |a Maegawa, H |e investigator |4 oth | |
| 700 | 1 | |a Nakamura, M |e investigator |4 oth | |
| 700 | 1 | |a Aoki, N |e investigator |4 oth | |
| 700 | 1 | |a Wu, Z S |e investigator |4 oth | |
| 700 | 1 | |a Yao, C H |e investigator |4 oth | |
| 700 | 1 | |a Wu, Z S |e investigator |4 oth | |
| 700 | 1 | |a Luszcz, Mary |e investigator |4 oth | |
| 700 | 1 | |a Welborn, T A |e investigator |4 oth | |
| 700 | 1 | |a Tang, Z |e investigator |4 oth | |
| 700 | 1 | |a Liu, L S |e investigator |4 oth | |
| 700 | 1 | |a Xie, J X |e investigator |4 oth | |
| 700 | 1 | |a Norton, R |e investigator |4 oth | |
| 700 | 1 | |a Ameratunga, S |e investigator |4 oth | |
| 700 | 1 | |a MacMahon, S |e investigator |4 oth | |
| 700 | 1 | |a Whitlock, G |e investigator |4 oth | |
| 700 | 1 | |a Knuiman, M W |e investigator |4 oth | |
| 700 | 1 | |a Christensen, H |e investigator |4 oth | |
| 700 | 1 | |a Wu, X G |e investigator |4 oth | |
| 700 | 1 | |a Zhou, J |e investigator |4 oth | |
| 700 | 1 | |a Yu, X H |e investigator |4 oth | |
| 700 | 1 | |a Tamakoshi, A |e investigator |4 oth | |
| 700 | 1 | |a Pan, W H |e investigator |4 oth | |
| 700 | 1 | |a Wu, Z L |e investigator |4 oth | |
| 700 | 1 | |a Chen, L Q |e investigator |4 oth | |
| 700 | 1 | |a Shan, G L |e investigator |4 oth | |
| 700 | 1 | |a Sritara, P |e investigator |4 oth | |
| 700 | 1 | |a Gu, D F |e investigator |4 oth | |
| 700 | 1 | |a Duan, X F |e investigator |4 oth | |
| 700 | 1 | |a MacMahon, S |e investigator |4 oth | |
| 700 | 1 | |a Norton, R |e investigator |4 oth | |
| 700 | 1 | |a Whitlock, G |e investigator |4 oth | |
| 700 | 1 | |a Jackson, R |e investigator |4 oth | |
| 700 | 1 | |a Li, Y H |e investigator |4 oth | |
| 700 | 1 | |a Lam, T H |e investigator |4 oth | |
| 700 | 1 | |a Jiang, C Q |e investigator |4 oth | |
| 700 | 1 | |a Kiyohara, Y |e investigator |4 oth | |
| 700 | 1 | |a Arima, H |e investigator |4 oth | |
| 700 | 1 | |a Iida, M |e investigator |4 oth | |
| 700 | 1 | |a Woo, J |e investigator |4 oth | |
| 700 | 1 | |a Ho, S C |e investigator |4 oth | |
| 700 | 1 | |a Hong, Z |e investigator |4 oth | |
| 700 | 1 | |a Huang, M S |e investigator |4 oth | |
| 700 | 1 | |a Zhou, B |e investigator |4 oth | |
| 700 | 1 | |a Fuh, J L |e investigator |4 oth | |
| 700 | 1 | |a Ueshima, H |e investigator |4 oth | |
| 700 | 1 | |a Kita, Y |e investigator |4 oth | |
| 700 | 1 | |a Choudhury, S R |e investigator |4 oth | |
| 700 | 1 | |a Suh, I |e investigator |4 oth | |
| 700 | 1 | |a Jee, S H |e investigator |4 oth | |
| 700 | 1 | |a Kim, I S |e investigator |4 oth | |
| 700 | 1 | |a Giles, G G |e investigator |4 oth | |
| 700 | 1 | |a Hashimoto, T |e investigator |4 oth | |
| 700 | 1 | |a Sakata, K |e investigator |4 oth | |
| 700 | 1 | |a Dobson, A |e investigator |4 oth | |
| 700 | 1 | |a Imai, Y |e investigator |4 oth | |
| 700 | 1 | |a Ohkubo, T |e investigator |4 oth | |
| 700 | 1 | |a Hozawa, A |e investigator |4 oth | |
| 700 | 1 | |a Jamrozik, K |e investigator |4 oth | |
| 700 | 1 | |a Hobbs, M |e investigator |4 oth | |
| 700 | 1 | |a Broadhurst, R |e investigator |4 oth | |
| 700 | 1 | |a Nakachi, K |e investigator |4 oth | |
| 700 | 1 | |a Fang, X H |e investigator |4 oth | |
| 700 | 1 | |a Li, S C |e investigator |4 oth | |
| 700 | 1 | |a Yang, Q D |e investigator |4 oth | |
| 700 | 1 | |a Chen, Z M |e investigator |4 oth | |
| 700 | 1 | |a Tanaka, H |e investigator |4 oth | |
| 700 | 1 | |a Kita, Y |e investigator |4 oth | |
| 700 | 1 | |a Nozaki, A |e investigator |4 oth | |
| 700 | 1 | |a Ueshima, H |e investigator |4 oth | |
| 700 | 1 | |a Horibe, H |e investigator |4 oth | |
| 700 | 1 | |a Matsutani, Y |e investigator |4 oth | |
| 700 | 1 | |a Kagaya, M |e investigator |4 oth | |
| 700 | 1 | |a Hughes, K |e investigator |4 oth | |
| 700 | 1 | |a Lee, J |e investigator |4 oth | |
| 700 | 1 | |a Heng, D |e investigator |4 oth | |
| 700 | 1 | |a Chew, S K |e investigator |4 oth | |
| 700 | 1 | |a Zhou, B F |e investigator |4 oth | |
| 700 | 1 | |a Zhang, H Y |e investigator |4 oth | |
| 700 | 1 | |a Shimamoto, K |e investigator |4 oth | |
| 700 | 1 | |a Saitoh, S |e investigator |4 oth | |
| 700 | 1 | |a Li, Z Z |e investigator |4 oth | |
| 700 | 1 | |a Zhang, H Y |e investigator |4 oth | |
| 700 | 1 | |a Norman, P |e investigator |4 oth | |
| 700 | 1 | |a Jamrozik, K |e investigator |4 oth | |
| 700 | 1 | |a He, Y |e investigator |4 oth | |
| 700 | 1 | |a Lam, T H |e investigator |4 oth | |
| 700 | 1 | |a Yao, S X |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t BMC cardiovascular disorders |d 2001 |g 14(2014) vom: 03. Mai, Seite 61 |w (DE-627)NLM11347802X |x 1471-2261 |7 nnns |
| 773 | 1 | 8 | |g volume:14 |g year:2014 |g day:03 |g month:05 |g pages:61 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1186/1471-2261-14-61 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 14 |j 2014 |b 03 |c 05 |h 61 | ||