Linezolid-induced lactic acidosis in two liver transplant patients with the mitochondrial DNA A2706G polymorphism
Copyright © 2014, American Society for Microbiology. All Rights Reserved..
Mitochondrial toxicity has been recently suggested to be the underlying mechanism of long-term linezolid-associated toxicity in patients with 16S rRNA genetic polymorphisms. Here, we report for the first time two cases of lactic acidosis due to long-term linezolid exposure in liver transplant recipients who presented an A2706G mitochondrial DNA polymorphism.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2014 |
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| Erschienen: |
2014 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:58 |
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| Enthalten in: |
Antimicrobial agents and chemotherapy - 58(2014), 7 vom: 01. Juli, Seite 4227-9 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Del Pozo, J L [VerfasserIn] |
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| Links: |
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| Themen: |
Acetamides |
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| Anmerkungen: |
Date Completed 10.09.2015 Date Revised 21.10.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1128/AAC.02856-14 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM237971704 |
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| 245 | 1 | 0 | |a Linezolid-induced lactic acidosis in two liver transplant patients with the mitochondrial DNA A2706G polymorphism |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2014, American Society for Microbiology. All Rights Reserved. | ||
| 520 | |a Mitochondrial toxicity has been recently suggested to be the underlying mechanism of long-term linezolid-associated toxicity in patients with 16S rRNA genetic polymorphisms. Here, we report for the first time two cases of lactic acidosis due to long-term linezolid exposure in liver transplant recipients who presented an A2706G mitochondrial DNA polymorphism | ||
| 650 | 4 | |a Case Reports | |
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| 700 | 1 | |a Yuste, J R |e verfasserin |4 aut | |
| 700 | 1 | |a Banales, J M |e verfasserin |4 aut | |
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