AduoLa Fuzhenglin down-regulates microwave-induced expression of β1-adrenergic receptor and muscarinic type 2 acetylcholine receptor in myocardial cells of rats
Copyright © 2014 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved..
This paper is aimed to study the effect of ADL on expression of β1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed to microwave radiation. ADL can protect rats against microwave-induced heart tissue injury.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2014 |
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Erschienen: |
2014 |
Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
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Enthalten in: |
Biomedical and environmental sciences : BES - 27(2014), 3 vom: 10. März, Seite 204-7 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Zhang, Jing [VerfasserIn] |
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Links: |
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Themen: |
Drugs, Chinese Herbal |
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Anmerkungen: |
Date Completed 14.08.2014 Date Revised 08.06.2018 published: Print Citation Status MEDLINE |
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doi: |
10.3967/bes2014.041 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM237143755 |
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520 | |a This paper is aimed to study the effect of ADL on expression of β1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed to microwave radiation. ADL can protect rats against microwave-induced heart tissue injury | ||
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650 | 7 | |a Receptor, Muscarinic M2 |2 NLM | |
650 | 7 | |a Receptors, Adrenergic, beta-1 |2 NLM | |
700 | 1 | |a Peng, Rui Yun |e verfasserin |4 aut | |
700 | 1 | |a Gao, Ya Bing |e verfasserin |4 aut | |
700 | 1 | |a Wang, Shui Ming |e verfasserin |4 aut | |
700 | 1 | |a Yang, Lei Lei |e verfasserin |4 aut | |
700 | 1 | |a Zhao, Li |e verfasserin |4 aut | |
700 | 1 | |a Dong, Ji |e verfasserin |4 aut | |
700 | 1 | |a Yao, Bin Wei |e verfasserin |4 aut | |
700 | 1 | |a Chang, Gong Min |e verfasserin |4 aut | |
700 | 1 | |a Xiong, Lu |e verfasserin |4 aut | |
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