AduoLa Fuzhenglin down-regulates microwave-induced expression of β1-adrenergic receptor and muscarinic type 2 acetylcholine receptor in myocardial cells of rats

Copyright © 2014 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved..

This paper is aimed to study the effect of ADL on expression of β1-AR and M2-AchR in myocardial cells of rats exposed to microwave radiation. Immunohistochemistry, Western blot and image analysis were used to detect the expression of β1-AR and M2-AchR in myocardial cells at 7 and 14 d after microwave exposure. The results show that the expression level was higher in microwave exposure group and 0.75 g/(kg•d) ADL group than in sham operation group and significantly lower in 1.5 and 3.0 g/(kg•d) ADL groups than in microwave group. So we have a conclusion that the expression of β1-AR and M2-AchR is down-regulated in myocardial cells of rats exposed to microwave radiation. ADL can protect rats against microwave-induced heart tissue injury.

Medienart:

E-Artikel

Erscheinungsjahr:

2014

Erschienen:

2014

Enthalten in:

Zur Gesamtaufnahme - volume:27

Enthalten in:

Biomedical and environmental sciences : BES - 27(2014), 3 vom: 10. März, Seite 204-7

Sprache:

Englisch

Beteiligte Personen:

Zhang, Jing [VerfasserIn]
Peng, Rui Yun [VerfasserIn]
Gao, Ya Bing [VerfasserIn]
Wang, Shui Ming [VerfasserIn]
Yang, Lei Lei [VerfasserIn]
Zhao, Li [VerfasserIn]
Dong, Ji [VerfasserIn]
Yao, Bin Wei [VerfasserIn]
Chang, Gong Min [VerfasserIn]
Xiong, Lu [VerfasserIn]

Links:

Volltext

Themen:

Drugs, Chinese Herbal
Journal Article
Protective Agents
Receptor, Muscarinic M2
Receptors, Adrenergic, beta-1

Anmerkungen:

Date Completed 14.08.2014

Date Revised 08.06.2018

published: Print

Citation Status MEDLINE

doi:

10.3967/bes2014.041

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM237143755