Gut ecosystem : how microbes help us

The human gut houses one of the most complex and abundant ecosystems composed of up to 1013-1014 microorganisms. Although the anthropocentric concept of life has concealed the function of microorganisms inside us, the important role of gut bacterial community in human health is well recognised today. Moreover, different microorganims, which are commonly present in a large diversity of food products, transit through our gut every day adding in some cases a beneficial effect to our health (probiotics). This crosstalk is concentrated mainly in the intestinal epithelium, where microbes provide the host with essential nutrients and modulation of the immune system. Furthermore, microorganisms also display antimicrobial activities maintaining a gut ecosystem stable. This review summarises some of the recent findings on the interaction of both commensal and probiotic bacteria with each other and with the host. The aim is to highlight the cooperative status found in healthy individuals as well as the importance of this crosstalk in the maintenance of human homeostasis.

Medienart:

E-Artikel

Erscheinungsjahr:

2014

Erschienen:

2014

Enthalten in:

Zur Gesamtaufnahme - volume:5

Enthalten in:

Beneficial microbes - 5(2014), 3 vom: 01. Sept., Seite 219-33

Sprache:

Englisch

Beteiligte Personen:

Martín, R [VerfasserIn]
Miquel, S [VerfasserIn]
Ulmer, J [VerfasserIn]
Langella, P [VerfasserIn]
Bermúdez-Humarán, L G [VerfasserIn]

Links:

Volltext

Themen:

Antimicrobial Cationic Peptides
Butyrates
Crosstalk bacteria-host
Human health
Immunomodulation
Journal Article
Microbiota
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 16.04.2015

Date Revised 10.06.2014

published: Print

Citation Status MEDLINE

doi:

10.3920/BM2013.0057

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM235983527