Prooxidative-antioxidative balance of cells in different types of renal replacement therapy
© 2014 S. Karger AG, Basel..
BACKGROUND: Patients suffering from chronic kidney disease (CKD) are exposed to increased oxidative stress and disturbances manifesting in the enzymatic and non-enzymatic antioxidative defence system. The object of the research was to assess the differences between conservative treatment, peritoneal dialysis and haemodialysis in moderating cellular antioxidative agents.
METHODS: The group examined comprised 145 patients. The activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glucose-6-phosphate dehydrogenase were obtained using kinetic methods. The spectrophotometric method established the concentrations of reduced glutathione, albumin, uric acid, glucose, total protein and lipids.
RESULTS: The type of treatment determined significant changes in antioxidative enzyme activities and concentrations of non-enzymatic antioxidative compounds.
CONCLUSIONS: Peritoneal dialysis provides better antioxidant protection than other types of therapy in CKD and should be considered as first-choice treatment despite more metabolic disorders.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2014 |
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| Erschienen: |
2014 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:37 |
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| Enthalten in: |
Blood purification - 37(2014), 1 vom: 29., Seite 4-11 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Stępniewska, Joanna [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 03.11.2014 Date Revised 19.03.2014 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1159/000356806 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM23500894X |
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| 041 | |a eng | ||
| 100 | 1 | |a Stępniewska, Joanna |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Prooxidative-antioxidative balance of cells in different types of renal replacement therapy |
| 264 | 1 | |c 2014 | |
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| 500 | |a Date Completed 03.11.2014 | ||
| 500 | |a Date Revised 19.03.2014 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2014 S. Karger AG, Basel. | ||
| 520 | |a BACKGROUND: Patients suffering from chronic kidney disease (CKD) are exposed to increased oxidative stress and disturbances manifesting in the enzymatic and non-enzymatic antioxidative defence system. The object of the research was to assess the differences between conservative treatment, peritoneal dialysis and haemodialysis in moderating cellular antioxidative agents | ||
| 520 | |a METHODS: The group examined comprised 145 patients. The activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase and glucose-6-phosphate dehydrogenase were obtained using kinetic methods. The spectrophotometric method established the concentrations of reduced glutathione, albumin, uric acid, glucose, total protein and lipids | ||
| 520 | |a RESULTS: The type of treatment determined significant changes in antioxidative enzyme activities and concentrations of non-enzymatic antioxidative compounds | ||
| 520 | |a CONCLUSIONS: Peritoneal dialysis provides better antioxidant protection than other types of therapy in CKD and should be considered as first-choice treatment despite more metabolic disorders | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Antioxidants |2 NLM | |
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| 650 | 7 | |a Uric Acid |2 NLM | |
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| 700 | 1 | |a Dołęgowska, Barbara |e verfasserin |4 aut | |
| 700 | 1 | |a Popińska, Marlena |e verfasserin |4 aut | |
| 700 | 1 | |a Sałata, Daria |e verfasserin |4 aut | |
| 700 | 1 | |a Budkowska, Marta |e verfasserin |4 aut | |
| 700 | 1 | |a Gołembiewska, Edyta |e verfasserin |4 aut | |
| 700 | 1 | |a Myślak, Marek |e verfasserin |4 aut | |
| 700 | 1 | |a Domański, Maciej |e verfasserin |4 aut | |
| 700 | 1 | |a Marchelek-Myśliwiec, Małgorzata |e verfasserin |4 aut | |
| 700 | 1 | |a Ciechanowski, Kazimierz |e verfasserin |4 aut | |
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