Viral infections in patients with an acute exacerbation of idiopathic interstitial pneumonia
Copyright © 2013 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved..
BACKGROUND: Patients with slowly progressive idiopathic interstitial pneumonia, including idiopathic pulmonary fibrosis, often deteriorate, thus suggesting that the clinical course may be unpredictable. Such episodes are termed acute exacerbation of idiopathic interstitial pneumonia. The etiology of an acute exacerbation of idiopathic interstitial pneumonia is unknown. In this study, we tested the hypothesis that an acute exacerbation of idiopathic interstitial pneumonia is induced by respiratory viral infections.
METHODS: Bronchoalveolar lavage fluid obtained from patients with an acute exacerbation of idiopathic interstitial pneumonia was tested for viral nucleic acid using polymerase chain reaction.
RESULTS: Only 1 of the 14 patients with an acute exacerbation of idiopathic interstitial pneumonia exhibited evidence of respiratory syncytial virus B, and 2 patients exhibited evidence of cytomegalovirus. Seven patients fulfilled the diagnostic criteria of idiopathic pulmonary fibrosis.
CONCLUSIONS: Most cases with an acute exacerbation of idiopathic interstitial pneumonia are not caused by a viral infection.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2014 |
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| Erschienen: |
2014 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:52 |
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| Enthalten in: |
Respiratory investigation - 52(2014), 1 vom: 24. Jan., Seite 65-70 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ushiki, Atsuhito [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 25.09.2014 Date Revised 21.10.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.resinv.2013.07.005 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM234140690 |
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| 245 | 1 | 0 | |a Viral infections in patients with an acute exacerbation of idiopathic interstitial pneumonia |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2013 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved. | ||
| 520 | |a BACKGROUND: Patients with slowly progressive idiopathic interstitial pneumonia, including idiopathic pulmonary fibrosis, often deteriorate, thus suggesting that the clinical course may be unpredictable. Such episodes are termed acute exacerbation of idiopathic interstitial pneumonia. The etiology of an acute exacerbation of idiopathic interstitial pneumonia is unknown. In this study, we tested the hypothesis that an acute exacerbation of idiopathic interstitial pneumonia is induced by respiratory viral infections | ||
| 520 | |a METHODS: Bronchoalveolar lavage fluid obtained from patients with an acute exacerbation of idiopathic interstitial pneumonia was tested for viral nucleic acid using polymerase chain reaction | ||
| 520 | |a RESULTS: Only 1 of the 14 patients with an acute exacerbation of idiopathic interstitial pneumonia exhibited evidence of respiratory syncytial virus B, and 2 patients exhibited evidence of cytomegalovirus. Seven patients fulfilled the diagnostic criteria of idiopathic pulmonary fibrosis | ||
| 520 | |a CONCLUSIONS: Most cases with an acute exacerbation of idiopathic interstitial pneumonia are not caused by a viral infection | ||
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| 700 | 1 | |a Hanaoka, Masayuki |e verfasserin |4 aut | |
| 700 | 1 | |a Kubo, Keishi |e verfasserin |4 aut | |
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