Postoperative management of Dupuytren's disease with topical nitroglycerin
Dupuytren's contracture remains a significant clinical challenge due to associated complications and a recurrence rate of up to 60%. Commonly, the operated skin tends to rebuild scar in the area of surgery. Assuming local ischemia as an etiological factor, two cases in which topical nitroglycerin was used following surgical treatment of Dupuytren's disease are presented. In these patients, no raised scar formation developed during healing. At least six months after surgery, disease recurrence was not noted and the patients and surgeon reported improved skin quality. In the present study, the use of topical nitroglycerin, a local vasodilator, appeared to prevent recurrent scar formation, possibly through prevention of local ischemia. Further study and follow-up is necessary.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2012 |
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| Erschienen: |
2012 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:20 |
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| Enthalten in: |
The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique - 20(2012), 4 vom: 01., Seite 249-50 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Emelife, Patrick I [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 02.12.2013 Date Revised 21.10.2021 published: Print Citation Status PubMed-not-MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM23324056X |
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| 245 | 1 | 0 | |a Postoperative management of Dupuytren's disease with topical nitroglycerin |
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| 500 | |a Date Revised 21.10.2021 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Dupuytren's contracture remains a significant clinical challenge due to associated complications and a recurrence rate of up to 60%. Commonly, the operated skin tends to rebuild scar in the area of surgery. Assuming local ischemia as an etiological factor, two cases in which topical nitroglycerin was used following surgical treatment of Dupuytren's disease are presented. In these patients, no raised scar formation developed during healing. At least six months after surgery, disease recurrence was not noted and the patients and surgeon reported improved skin quality. In the present study, the use of topical nitroglycerin, a local vasodilator, appeared to prevent recurrent scar formation, possibly through prevention of local ischemia. Further study and follow-up is necessary | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Dupuytren | |
| 650 | 4 | |a Scar | |
| 650 | 4 | |a Surgery | |
| 650 | 4 | |a Topical nitroglycerin | |
| 700 | 1 | |a Kling, Russell E |e verfasserin |4 aut | |
| 700 | 1 | |a Wollstein, Ronit |e verfasserin |4 aut | |
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