Sick sinus syndrome possibly due to lopinavir-ritonavir : report of two cases
We describe herein two cases of sick sinus syndrome possibly due to lopinavir-ritonavir in HIV-infected individuals. The heart rate dropped to 30 to 40 beats per minute in both cases, but patients remained asymptomatic and recovered promptly after discontinuation of lopinavir-ritonavir. The time until onset varied; one patient developed bradyarrhythmia 9 days after the initial dose, and another 4 hours after. Since lopinavir-ritonavir is a frequently used antiretroviral agent, clinicians must be aware of this potentially lethal adverse effect.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2013 |
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| Erschienen: |
2013 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:87 |
|---|---|
| Enthalten in: |
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases - 87(2013), 5 vom: 16. Sept., Seite 613-7 |
| Sprache: |
Japanisch |
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| Beteiligte Personen: |
Sasaki, Shugo [VerfasserIn] |
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| Themen: |
2494G1JF75 |
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| Anmerkungen: |
Date Completed 09.01.2014 Date Revised 23.08.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM232331677 |
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| 100 | 1 | |a Sasaki, Shugo |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Sick sinus syndrome possibly due to lopinavir-ritonavir |b report of two cases |
| 264 | 1 | |c 2013 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 09.01.2014 | ||
| 500 | |a Date Revised 23.08.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a We describe herein two cases of sick sinus syndrome possibly due to lopinavir-ritonavir in HIV-infected individuals. The heart rate dropped to 30 to 40 beats per minute in both cases, but patients remained asymptomatic and recovered promptly after discontinuation of lopinavir-ritonavir. The time until onset varied; one patient developed bradyarrhythmia 9 days after the initial dose, and another 4 hours after. Since lopinavir-ritonavir is a frequently used antiretroviral agent, clinicians must be aware of this potentially lethal adverse effect | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Anti-Retroviral Agents |2 NLM | |
| 650 | 7 | |a Lopinavir |2 NLM | |
| 650 | 7 | |a 2494G1JF75 |2 NLM | |
| 650 | 7 | |a Ritonavir |2 NLM | |
| 650 | 7 | |a O3J8G9O825 |2 NLM | |
| 700 | 1 | |a Yanagisawa, Naoki |e verfasserin |4 aut | |
| 700 | 1 | |a Suganuma, Akihiko |e verfasserin |4 aut | |
| 700 | 1 | |a Imamura, Akifumi |e verfasserin |4 aut | |
| 700 | 1 | |a Ajisawa, Atsushi |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases |d 1970 |g 87(2013), 5 vom: 16. Sept., Seite 613-7 |w (DE-627)NLM000193976 |x 0387-5911 |7 nnns |
| 773 | 1 | 8 | |g volume:87 |g year:2013 |g number:5 |g day:16 |g month:09 |g pages:613-7 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 87 |j 2013 |e 5 |b 16 |c 09 |h 613-7 | ||