Associated morbidity of nasolacrimal duct obstruction--a large community based case-control study
BACKGROUND: To evaluate the prevalence and risk factors of various conditions among patients with nasolacrimal duct obstruction (NLDO).
METHODS: A retrospective, observational case control study of 2,615 patients diagnosed with NLDO in the Central District of Clalit Health Services HMO in Israel, from 2003 to 2012; 15,650 control patients were randomly selected from the district HMO members. Medical and socio-demographic information were extracted from patients' electronic medical records. The prevalence of various ocular and systemic conditions as risk factors for NLDO was calculated.
RESULTS: The average age of NLDO patients was 68.3 ± 14.9 years, 34.4 % were male. Age (p < 0.001), ischemic heart disease (OR = 1.29; CI: 1.15-1.44), glaucoma (OR = 1.17; CI: 1.01-1.36), allergic conjunctivitis (OR = 3.59; CI: 3.28-3.94), dry eye (OR = 1.43; CI: 1.31-1.58), epiphora (OR = 6.34; CI: 5.09-7.91), and allergic rhinitis (OR = 1.51; CI: 1.33-1.71) were significantly associated with NLDO. Smoking (OR = 0.86; CI: 0.77-0.96) was significantly less prevalent among NLDO patients.
CONCLUSIONS: The etiology of NLDO is multifactorial. The prevalence of associated demographic, systemic, and periocular conditions varies. A better understanding of the patho-physiological association between these factors and NLDO may help its prevention and treatment.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2014 |
---|---|
Erschienen: |
2014 |
Enthalten in: |
Zur Gesamtaufnahme - volume:252 |
---|---|
Enthalten in: |
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 252(2014), 1 vom: 01. Jan., Seite 125-30 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Nemet, Arie Y [VerfasserIn] |
---|
Links: |
---|
Themen: |
---|
Anmerkungen: |
Date Completed 18.06.2014 Date Revised 21.10.2021 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1007/s00417-013-2484-3 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM23189015X |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM23189015X | ||
003 | DE-627 | ||
005 | 20231224091804.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231224s2014 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1007/s00417-013-2484-3 |2 doi | |
028 | 5 | 2 | |a pubmed24n0773.xml |
035 | |a (DE-627)NLM23189015X | ||
035 | |a (NLM)24146269 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Nemet, Arie Y |e verfasserin |4 aut | |
245 | 1 | 0 | |a Associated morbidity of nasolacrimal duct obstruction--a large community based case-control study |
264 | 1 | |c 2014 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 18.06.2014 | ||
500 | |a Date Revised 21.10.2021 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a BACKGROUND: To evaluate the prevalence and risk factors of various conditions among patients with nasolacrimal duct obstruction (NLDO) | ||
520 | |a METHODS: A retrospective, observational case control study of 2,615 patients diagnosed with NLDO in the Central District of Clalit Health Services HMO in Israel, from 2003 to 2012; 15,650 control patients were randomly selected from the district HMO members. Medical and socio-demographic information were extracted from patients' electronic medical records. The prevalence of various ocular and systemic conditions as risk factors for NLDO was calculated | ||
520 | |a RESULTS: The average age of NLDO patients was 68.3 ± 14.9 years, 34.4 % were male. Age (p < 0.001), ischemic heart disease (OR = 1.29; CI: 1.15-1.44), glaucoma (OR = 1.17; CI: 1.01-1.36), allergic conjunctivitis (OR = 3.59; CI: 3.28-3.94), dry eye (OR = 1.43; CI: 1.31-1.58), epiphora (OR = 6.34; CI: 5.09-7.91), and allergic rhinitis (OR = 1.51; CI: 1.33-1.71) were significantly associated with NLDO. Smoking (OR = 0.86; CI: 0.77-0.96) was significantly less prevalent among NLDO patients | ||
520 | |a CONCLUSIONS: The etiology of NLDO is multifactorial. The prevalence of associated demographic, systemic, and periocular conditions varies. A better understanding of the patho-physiological association between these factors and NLDO may help its prevention and treatment | ||
650 | 4 | |a Journal Article | |
700 | 1 | |a Vinker, Shlomo |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie |d 1985 |g 252(2014), 1 vom: 01. Jan., Seite 125-30 |w (DE-627)NLM01296803X |x 1435-702X |7 nnns |
773 | 1 | 8 | |g volume:252 |g year:2014 |g number:1 |g day:01 |g month:01 |g pages:125-30 |
856 | 4 | 0 | |u http://dx.doi.org/10.1007/s00417-013-2484-3 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 252 |j 2014 |e 1 |b 01 |c 01 |h 125-30 |