IFITMs restrict the replication of multiple pathogenic viruses

© 2013..

The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis.

Medienart:

E-Artikel

Erscheinungsjahr:

2013

Erschienen:

2013

Enthalten in:

Zur Gesamtaufnahme - volume:425

Enthalten in:

Journal of molecular biology - 425(2013), 24 vom: 13. Dez., Seite 4937-55

Sprache:

Englisch

Beteiligte Personen:

Perreira, Jill M [VerfasserIn]
Chin, Christopher R [VerfasserIn]
Feeley, Eric M [VerfasserIn]
Brass, Abraham L [VerfasserIn]

Links:

Volltext

Themen:

9008-11-1
AS
Alanine scanning
Antigens, Differentiation
CCHFV
CD225 family
CIL
CMEM
Clathrin-mediated endocytosis motif
Conserved intracellular loop
Crimean Congo hemorrhagic fever virus
DENV
Dengue virus
EBOV
Ebola virus
GP
Glycoprotein
HCV
HIV-1
Hepatitis C virus
Host virus interactions
Human immunodeficiency virus type 1
IAV
IFITM
IFN
Influenza A virus
Interferon
Interferon effector genes
Interferon-inducible transmembrane protein
Interferons
JSRV
Jaagsiekte sheep retrovirus
Journal Article
Leu-13 antigen
MARV
MLV
MS
Marburg virus
Mass spectrometry
Membrane Proteins
Moloney leukemia virus
N-terminal domain
NTD
OSBP
Oxysterol binding protein
RVFV
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Restriction factor
Review
Rift Valley fever virus
SARS CoV
SeV
Sendai virus
Severe acute respiratory syndrome coronavirus
VAPA
Vesicle-associated membrane protein-A

Anmerkungen:

Date Completed 15.01.2014

Date Revised 31.03.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.jmb.2013.09.024

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM231251890