Cardiomyocyte differentiation of individual clones murine induced pluripotent stem cells
Cardiomyocyte differentiation of certain clones of murine induced pluripotent stem cells (iPS) was estimated. iPS were obtained due to reprogramming of murine embryonic fibroblasts with transposon-based Sleeping beauty plasmids as sene delivery systems. Differentiation was performed in suspension culture and in attached to tissue-culture plates embryoid bodies (EBs). Ascorbic acid was applied as inductor. According to the obtained results, the differentiation was tenfold more effective in attached EBs. Ascorbic acid stimulated the generation of cardiomiocytes.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2013 |
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| Erschienen: |
2013 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:59 |
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| Enthalten in: |
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) - 59(2013), 3 vom: 04., Seite 10-7 |
| Sprache: |
Ukrainisch |
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| Beteiligte Personen: |
Malysheva, S V [VerfasserIn] |
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| Themen: |
147336-22-9 |
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| Anmerkungen: |
Date Completed 03.09.2013 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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NLM230138535 |
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| 245 | 1 | 0 | |a Cardiomyocyte differentiation of individual clones murine induced pluripotent stem cells |
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| 500 | |a Date Completed 03.09.2013 | ||
| 500 | |a Date Revised 21.11.2013 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Cardiomyocyte differentiation of certain clones of murine induced pluripotent stem cells (iPS) was estimated. iPS were obtained due to reprogramming of murine embryonic fibroblasts with transposon-based Sleeping beauty plasmids as sene delivery systems. Differentiation was performed in suspension culture and in attached to tissue-culture plates embryoid bodies (EBs). Ascorbic acid was applied as inductor. According to the obtained results, the differentiation was tenfold more effective in attached EBs. Ascorbic acid stimulated the generation of cardiomiocytes | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Bil'ko, N M |e verfasserin |4 aut | |
| 700 | 1 | |a Heschheller, J |e verfasserin |4 aut | |
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