Effect of repeated oral administration of bifenthrin on lipid peroxidation and anti-oxidant parameters in Wistar rats
The oxidative stress-inducing potential of the pyrethroid insecticide, bifenthrin, was evaluated in rats at 5.8 mg/kg body weight once daily for 20 or 30 days. Bifenthrin treated animals showed significantly increased lipid peroxidation, evidenced by increased blood malondialdehyde levels. Blood glutathione levels and activities of catalase and glutathione peroxidase decreased significantly in the bifenthrin treated animals after both 20 and 30 days of treatment, whereas, the activities of superoxide dismutase and glutathione S-transferase decreased significantly only on the 30th day. In conclusion, bifenthrin has a potential to induce severe oxidative stress in rats exposed to sublethal concentrations.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2013 |
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| Erschienen: |
2013 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:91 |
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| Enthalten in: |
Bulletin of environmental contamination and toxicology - 91(2013), 1 vom: 24. Juli, Seite 125-8 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Dar, Muneer Ahmad [VerfasserIn] |
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| Links: |
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| Themen: |
6B66JED0KN |
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| Anmerkungen: |
Date Completed 07.02.2014 Date Revised 26.06.2013 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00128-013-1022-7 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM227986474 |
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| 245 | 1 | 0 | |a Effect of repeated oral administration of bifenthrin on lipid peroxidation and anti-oxidant parameters in Wistar rats |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The oxidative stress-inducing potential of the pyrethroid insecticide, bifenthrin, was evaluated in rats at 5.8 mg/kg body weight once daily for 20 or 30 days. Bifenthrin treated animals showed significantly increased lipid peroxidation, evidenced by increased blood malondialdehyde levels. Blood glutathione levels and activities of catalase and glutathione peroxidase decreased significantly in the bifenthrin treated animals after both 20 and 30 days of treatment, whereas, the activities of superoxide dismutase and glutathione S-transferase decreased significantly only on the 30th day. In conclusion, bifenthrin has a potential to induce severe oxidative stress in rats exposed to sublethal concentrations | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Antioxidants |2 NLM | |
| 650 | 7 | |a Environmental Pollutants |2 NLM | |
| 650 | 7 | |a Insecticides |2 NLM | |
| 650 | 7 | |a Pyrethrins |2 NLM | |
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| 650 | 7 | |a 6B66JED0KN |2 NLM | |
| 700 | 1 | |a Khan, Adil Mehraj |e verfasserin |4 aut | |
| 700 | 1 | |a Raina, Rajinder |e verfasserin |4 aut | |
| 700 | 1 | |a Verma, Pawan Kumar |e verfasserin |4 aut | |
| 700 | 1 | |a Sultana, Mudasir |e verfasserin |4 aut | |
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