Insights on GRACE (Gender, Race, And Clinical Experience) from the patient's perspective : GRACE participant survey
The Gender, Race And Clinical Experience (GRACE) study was conducted between October 2006 and December 2008 to evaluate sex- and race-based differences in outcomes after treatment with a darunavir/ritonavir-based antiretroviral regimen. Between June 2010 and June 2011, former participants of the GRACE trial at participating sites were asked to complete a 40-item questionnaire as part of the GRACE Participant Survey study, with a primary objective of assessing patients' characteristics, experiences, and opinions about participation in GRACE. Of 243 potential survey respondents, 151 (62%) completed the survey. Respondents were representative of the overall GRACE population and were predominantly female (64%); fewer were black, and more reported recreational drug use compared with nonrespondents (55% vs. 62% and 17% vs. 10%, respectively). Access to treatment (41%) and too many blood draws (26%) were reported as the best and worst part of GRACE, respectively. Support from study site staff was reported as the most important factor in completing the study (47%). Factors associated with nonadherence, study discontinuation, and poor virologic response in univariate analyses were being the primary caregiver for children, unemployment, and transportation difficulties, respectively. Patients with these characteristics may be at risk of poor study outcomes and may benefit from additional adherence and retention strategies in future studies and routine clinical care.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2013 |
|---|---|
| Erschienen: |
2013 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
|---|---|
| Enthalten in: |
AIDS patient care and STDs - 27(2013), 6 vom: 18. Juni, Seite 352-62 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Squires, Kathleen [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Darunavir |
|---|
| Anmerkungen: |
Date Completed 30.07.2013 Date Revised 17.03.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1089/apc.2013.0015 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM227732871 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM227732871 | ||
| 003 | DE-627 | ||
| 005 | 20231224074339.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1089/apc.2013.0015 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0759.xml |
| 035 | |a (DE-627)NLM227732871 | ||
| 035 | |a (NLM)23701200 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Squires, Kathleen |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Insights on GRACE (Gender, Race, And Clinical Experience) from the patient's perspective |b GRACE participant survey |
| 264 | 1 | |c 2013 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 30.07.2013 | ||
| 500 | |a Date Revised 17.03.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The Gender, Race And Clinical Experience (GRACE) study was conducted between October 2006 and December 2008 to evaluate sex- and race-based differences in outcomes after treatment with a darunavir/ritonavir-based antiretroviral regimen. Between June 2010 and June 2011, former participants of the GRACE trial at participating sites were asked to complete a 40-item questionnaire as part of the GRACE Participant Survey study, with a primary objective of assessing patients' characteristics, experiences, and opinions about participation in GRACE. Of 243 potential survey respondents, 151 (62%) completed the survey. Respondents were representative of the overall GRACE population and were predominantly female (64%); fewer were black, and more reported recreational drug use compared with nonrespondents (55% vs. 62% and 17% vs. 10%, respectively). Access to treatment (41%) and too many blood draws (26%) were reported as the best and worst part of GRACE, respectively. Support from study site staff was reported as the most important factor in completing the study (47%). Factors associated with nonadherence, study discontinuation, and poor virologic response in univariate analyses were being the primary caregiver for children, unemployment, and transportation difficulties, respectively. Patients with these characteristics may be at risk of poor study outcomes and may benefit from additional adherence and retention strategies in future studies and routine clinical care | ||
| 650 | 4 | |a Evaluation Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a HIV Protease Inhibitors |2 NLM | |
| 650 | 7 | |a Sulfonamides |2 NLM | |
| 650 | 7 | |a Ritonavir |2 NLM | |
| 650 | 7 | |a O3J8G9O825 |2 NLM | |
| 650 | 7 | |a Darunavir |2 NLM | |
| 650 | 7 | |a YO603Y8113 |2 NLM | |
| 700 | 1 | |a Feinberg, Judith |e verfasserin |4 aut | |
| 700 | 1 | |a Bridge, Dawn Averitt |e verfasserin |4 aut | |
| 700 | 1 | |a Currier, Judith |e verfasserin |4 aut | |
| 700 | 1 | |a Ryan, Robert |e verfasserin |4 aut | |
| 700 | 1 | |a Seyedkazemi, Setareh |e verfasserin |4 aut | |
| 700 | 1 | |a Dayaram, Yaswant K |e verfasserin |4 aut | |
| 700 | 1 | |a Mrus, Joseph |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t AIDS patient care and STDs |d 1996 |g 27(2013), 6 vom: 18. Juni, Seite 352-62 |w (DE-627)NLM09547725X |x 1557-7449 |7 nnns |
| 773 | 1 | 8 | |g volume:27 |g year:2013 |g number:6 |g day:18 |g month:06 |g pages:352-62 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1089/apc.2013.0015 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 27 |j 2013 |e 6 |b 18 |c 06 |h 352-62 | ||