Toward patient-specific simulations of cardiac valves : state-of-the-art and future directions

Copyright © 2012 Elsevier Ltd. All rights reserved..

Recent computational methods enabling patient-specific simulations of native and prosthetic heart valves are reviewed. Emphasis is placed on two critical components of such methods: (1) anatomically realistic finite element models for simulating the structural dynamics of heart valves; and (2) fluid structure interaction methods for simulating the performance of heart valves in a patient-specific beating left ventricle. It is shown that the significant progress achieved in both fronts paves the way toward clinically relevant computational models that can simulate the performance of a range of heart valves, native and prosthetic, in a patient-specific left heart environment. The significant algorithmic and model validation challenges that need to be tackled in the future to realize this goal are also discussed.

Medienart:

E-Artikel

Erscheinungsjahr:

2013

Erschienen:

2013

Enthalten in:

Zur Gesamtaufnahme - volume:46

Enthalten in:

Journal of biomechanics - 46(2013), 2 vom: 18. Jan., Seite 217-28

Sprache:

Englisch

Beteiligte Personen:

Votta, Emiliano [VerfasserIn]
Le, Trung Bao [VerfasserIn]
Stevanella, Marco [VerfasserIn]
Fusini, Laura [VerfasserIn]
Caiani, Enrico G [VerfasserIn]
Redaelli, Alberto [VerfasserIn]
Sotiropoulos, Fotis [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 04.07.2013

Date Revised 21.10.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.jbiomech.2012.10.026

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM222830379