Inequalities in HIV disease management and progression in migrants from Latin America and sub-Saharan Africa living in Spain
© 2012 British HIV Association..
OBJECTIVES: The objective of the study was to analyse key HIV-related outcomes in migrants originating from Latin America and the Spanish-speaking Caribbean (LAC) or sub-Saharan Africa (SSA) living in Spain compared with native Spaniards (NSP).
METHODS: The Cohort of the Spanish AIDS Research Network (CoRIS) is an open, prospective, multicentre cohort of antiretroviral-naïve patients representing 13 of the 17 Spanish regions. The study period was 2004-2010. Multivariate logistic or Fine and Gray regression models were fitted as appropriate to estimate the adjusted effect of region of origin on the different outcomes.
RESULTS: Of the 6811 subjects in CoRIS, 6278 were NSP (74.2%), LAC (19.4%) or SSA (6.4%). For these patients, the follow-up time was 15870 person-years. Compared with NSP, SSA and LAC under 35 years of age had a higher risk of delayed diagnosis [odds ratio (OR) 2.0 (95% confidence interval (CI) 1.5-2.8) and OR 1.7 (95% CI 1.4-2.1), respectively], as did LAC aged 35-50 years [OR 1.3 (95% CI 1.0-1.6)]. There were no major differences in time to antiretroviral therapy (ART) requirement or initiation. SSA exhibited a poorer immunological and virological response [hazard ratio (HR) [corrected] 0.8 (95% CI 0.7-1.0) and HR [corrected] 0.7 (95% CI 0.6-0.9), respectively], while no difference was found for LAC. SSA and LAC showed an increased risk of AIDS for ages between 35 and 50 years [HR 2.0 (95% CI 1.1-3.7) and HR [corrected] 1.6 (95% CI 1.1-2.4), respectively], which was attributable to a higher incidence of tuberculosis. However, no statistically significant differences were observed in mortality.
CONCLUSIONS: Migrants experience a disproportionate diagnostic delay, but no meaningful inequalities were identified regarding initiation of treatment after diagnosis. A poorer virological and immunological response was observed in SSA. Migrants had an increased risk of AIDS, which was mainly attributable to tuberculosis.
| Errataetall: | |
|---|---|
| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2013 |
|---|---|
| Erschienen: |
2013 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
|---|---|
| Enthalten in: |
HIV medicine - 14(2013), 5 vom: 21. Mai, Seite 273-83 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Monge, S [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Anti-HIV Agents |
|---|
| Anmerkungen: |
Date Completed 30.09.2013 Date Revised 20.04.2015 published: Print-Electronic ErratumIn: HIV Med. 2014 Jan;15(1):64 Citation Status MEDLINE |
|---|
| doi: |
10.1111/hiv.12001 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM222799390 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM222799390 | ||
| 003 | DE-627 | ||
| 005 | 20231224055135.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/hiv.12001 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0742.xml |
| 035 | |a (DE-627)NLM222799390 | ||
| 035 | |a (NLM)23171059 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Monge, S |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Inequalities in HIV disease management and progression in migrants from Latin America and sub-Saharan Africa living in Spain |
| 264 | 1 | |c 2013 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 30.09.2013 | ||
| 500 | |a Date Revised 20.04.2015 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a ErratumIn: HIV Med. 2014 Jan;15(1):64 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2012 British HIV Association. | ||
| 520 | |a OBJECTIVES: The objective of the study was to analyse key HIV-related outcomes in migrants originating from Latin America and the Spanish-speaking Caribbean (LAC) or sub-Saharan Africa (SSA) living in Spain compared with native Spaniards (NSP) | ||
| 520 | |a METHODS: The Cohort of the Spanish AIDS Research Network (CoRIS) is an open, prospective, multicentre cohort of antiretroviral-naïve patients representing 13 of the 17 Spanish regions. The study period was 2004-2010. Multivariate logistic or Fine and Gray regression models were fitted as appropriate to estimate the adjusted effect of region of origin on the different outcomes | ||
| 520 | |a RESULTS: Of the 6811 subjects in CoRIS, 6278 were NSP (74.2%), LAC (19.4%) or SSA (6.4%). For these patients, the follow-up time was 15870 person-years. Compared with NSP, SSA and LAC under 35 years of age had a higher risk of delayed diagnosis [odds ratio (OR) 2.0 (95% confidence interval (CI) 1.5-2.8) and OR 1.7 (95% CI 1.4-2.1), respectively], as did LAC aged 35-50 years [OR 1.3 (95% CI 1.0-1.6)]. There were no major differences in time to antiretroviral therapy (ART) requirement or initiation. SSA exhibited a poorer immunological and virological response [hazard ratio (HR) [corrected] 0.8 (95% CI 0.7-1.0) and HR [corrected] 0.7 (95% CI 0.6-0.9), respectively], while no difference was found for LAC. SSA and LAC showed an increased risk of AIDS for ages between 35 and 50 years [HR 2.0 (95% CI 1.1-3.7) and HR [corrected] 1.6 (95% CI 1.1-2.4), respectively], which was attributable to a higher incidence of tuberculosis. However, no statistically significant differences were observed in mortality | ||
| 520 | |a CONCLUSIONS: Migrants experience a disproportionate diagnostic delay, but no meaningful inequalities were identified regarding initiation of treatment after diagnosis. A poorer virological and immunological response was observed in SSA. Migrants had an increased risk of AIDS, which was mainly attributable to tuberculosis | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Anti-HIV Agents |2 NLM | |
| 700 | 1 | |a Alejos, B |e verfasserin |4 aut | |
| 700 | 1 | |a Dronda, F |e verfasserin |4 aut | |
| 700 | 1 | |a Del Romero, J |e verfasserin |4 aut | |
| 700 | 1 | |a Iribarren, J A |e verfasserin |4 aut | |
| 700 | 1 | |a Pulido, F |e verfasserin |4 aut | |
| 700 | 1 | |a Rubio, R |e verfasserin |4 aut | |
| 700 | 1 | |a Miró, J M |e verfasserin |4 aut | |
| 700 | 1 | |a Gutierrez, F |e verfasserin |4 aut | |
| 700 | 1 | |a Del Amo, J |e verfasserin |4 aut | |
| 700 | 0 | |a CoRIS |e verfasserin |4 aut | |
| 700 | 1 | |a Berenguer, Juan |e investigator |4 oth | |
| 700 | 1 | |a del Amo, Julia |e investigator |4 oth | |
| 700 | 1 | |a García, Federico |e investigator |4 oth | |
| 700 | 1 | |a Gutiérrez, Félix |e investigator |4 oth | |
| 700 | 1 | |a Labarga, Pablo |e investigator |4 oth | |
| 700 | 1 | |a Moreno, Santiago |e investigator |4 oth | |
| 700 | 1 | |a Muñoz, María Ángeles |e investigator |4 oth | |
| 700 | 1 | |a Sobrino, Paz |e investigator |4 oth | |
| 700 | 1 | |a Alejos, Belen |e investigator |4 oth | |
| 700 | 1 | |a Hernando, Victoria |e investigator |4 oth | |
| 700 | 1 | |a Alvarez, Debora |e investigator |4 oth | |
| 700 | 1 | |a Monge, Susana |e investigator |4 oth | |
| 700 | 1 | |a Jarrin, Inma |e investigator |4 oth | |
| 700 | 1 | |a Muñoz, María Ángeles |e investigator |4 oth | |
| 700 | 1 | |a García- Merino, Isabel |e investigator |4 oth | |
| 700 | 1 | |a Gómez, Coral |e investigator |4 oth | |
| 700 | 1 | |a Gallego, Jorge |e investigator |4 oth | |
| 700 | 1 | |a García, Almudena |e investigator |4 oth | |
| 700 | 1 | |a Sogorb, Joaquín Portilla |e investigator |4 oth | |
| 700 | 1 | |a Merino de Lucas, Esperanza |e investigator |4 oth | |
| 700 | 1 | |a Bañuls, Sergio Reus |e investigator |4 oth | |
| 700 | 1 | |a Martínez, Vicente Boix |e investigator |4 oth | |
| 700 | 1 | |a Oncina, Livia Giner |e investigator |4 oth | |
| 700 | 1 | |a Pastor, Carmen Gadea |e investigator |4 oth | |
| 700 | 1 | |a Tamarit, Irene Portilla |e investigator |4 oth | |
| 700 | 1 | |a Toledo, Patricia Arcaina |e investigator |4 oth | |
| 700 | 1 | |a Gómez Sirvent, Juan Luis |e investigator |4 oth | |
| 700 | 1 | |a Rodríguez Fortúnez, Patricia |e investigator |4 oth | |
| 700 | 1 | |a Remedios, María |e investigator |4 oth | |
| 700 | 1 | |a Valls, Alemán |e investigator |4 oth | |
| 700 | 1 | |a del Mar Alonso Socas, María |e investigator |4 oth | |
| 700 | 1 | |a María, Ana |e investigator |4 oth | |
| 700 | 1 | |a Lirola, López |e investigator |4 oth | |
| 700 | 1 | |a Hernández, María Inmaculada Hernández |e investigator |4 oth | |
| 700 | 1 | |a Díaz-Flores, Felicitas |e investigator |4 oth | |
| 700 | 1 | |a Soriano, Vicente |e investigator |4 oth | |
| 700 | 1 | |a Labarga, Pablo |e investigator |4 oth | |
| 700 | 1 | |a Barreiro, Pablo |e investigator |4 oth | |
| 700 | 1 | |a Rivas, Pablo |e investigator |4 oth | |
| 700 | 1 | |a Blanco, Francisco |e investigator |4 oth | |
| 700 | 1 | |a Carbonero, Luz Martín |e investigator |4 oth | |
| 700 | 1 | |a Vispo, Eugenia |e investigator |4 oth | |
| 700 | 1 | |a Solera, Carmen |e investigator |4 oth | |
| 700 | 1 | |a Asensi, Victor |e investigator |4 oth | |
| 700 | 1 | |a Valle, Eulalia |e investigator |4 oth | |
| 700 | 1 | |a Antonio, José |e investigator |4 oth | |
| 700 | 1 | |a Miró, José M |e investigator |4 oth | |
| 700 | 1 | |a López-Dieguez, María |e investigator |4 oth | |
| 700 | 1 | |a Manzardo, Christian |e investigator |4 oth | |
| 700 | 1 | |a Zamora, Laura |e investigator |4 oth | |
| 700 | 1 | |a Pérez, Iñaki |e investigator |4 oth | |
| 700 | 1 | |a García, Ma Teresa |e investigator |4 oth | |
| 700 | 1 | |a Ligero, Carmen |e investigator |4 oth | |
| 700 | 1 | |a Blanco, José Luis |e investigator |4 oth | |
| 700 | 1 | |a García-Alcaide, Felipe |e investigator |4 oth | |
| 700 | 1 | |a Martínez, Esteban |e investigator |4 oth | |
| 700 | 1 | |a Mallolas, Josep |e investigator |4 oth | |
| 700 | 1 | |a Gatell, José M |e investigator |4 oth | |
| 700 | 1 | |a Rubio, Rafael |e investigator |4 oth | |
| 700 | 1 | |a Pulido, Federico |e investigator |4 oth | |
| 700 | 1 | |a Fiorante, Silvana |e investigator |4 oth | |
| 700 | 1 | |a Llenas, Jara |e investigator |4 oth | |
| 700 | 1 | |a Rodríguez, Violeta |e investigator |4 oth | |
| 700 | 1 | |a Matarranz, Mariano |e investigator |4 oth | |
| 700 | 1 | |a Iribarren, José Antonio |e investigator |4 oth | |
| 700 | 1 | |a Arrizabalaga, Julio |e investigator |4 oth | |
| 700 | 1 | |a Aramburu, María José |e investigator |4 oth | |
| 700 | 1 | |a Camino, Xabier |e investigator |4 oth | |
| 700 | 1 | |a Rodríguez-Arrondo, Francisco |e investigator |4 oth | |
| 700 | 1 | |a von Wichmann, Miguel Ángel |e investigator |4 oth | |
| 700 | 1 | |a Tomé, Lidia Pascual |e investigator |4 oth | |
| 700 | 1 | |a Goenaga, Miguel Ángel |e investigator |4 oth | |
| 700 | 1 | |a Bustinduy, Ma Jesús |e investigator |4 oth | |
| 700 | 1 | |a Galparsoro, Harkaitz Azkune |e investigator |4 oth | |
| 700 | 1 | |a Gutiérrez, Félix |e investigator |4 oth | |
| 700 | 1 | |a Masiá, Mar |e investigator |4 oth | |
| 700 | 1 | |a Ramos, José Manuel |e investigator |4 oth | |
| 700 | 1 | |a Padilla, Sergio |e investigator |4 oth | |
| 700 | 1 | |a Navarro, Andrés |e investigator |4 oth | |
| 700 | 1 | |a Montolio, Fernando |e investigator |4 oth | |
| 700 | 1 | |a Peral, Yolanda |e investigator |4 oth | |
| 700 | 1 | |a García, Catalina Robledano |e investigator |4 oth | |
| 700 | 1 | |a Clotet, Bonaventura |e investigator |4 oth | |
| 700 | 1 | |a Tural, Cristina |e investigator |4 oth | |
| 700 | 1 | |a Ruiz, Lidia |e investigator |4 oth | |
| 700 | 1 | |a Miranda, Cristina |e investigator |4 oth | |
| 700 | 1 | |a Muga, Roberto |e investigator |4 oth | |
| 700 | 1 | |a Tor, Jordi |e investigator |4 oth | |
| 700 | 1 | |a Sanvisens, Arantza |e investigator |4 oth | |
| 700 | 1 | |a Berenguer, Juan |e investigator |4 oth | |
| 700 | 1 | |a López Bernaldo de Quirós, Juan Carlos |e investigator |4 oth | |
| 700 | 1 | |a Miralles, Pilar |e investigator |4 oth | |
| 700 | 1 | |a Ochaíta, Jaime Cosín |e investigator |4 oth | |
| 700 | 1 | |a Conde, Matilde Sánchez |e investigator |4 oth | |
| 700 | 1 | |a Cuellar, Isabel Gutiérrez |e investigator |4 oth | |
| 700 | 1 | |a Schacke, Margarita Ramírez |e investigator |4 oth | |
| 700 | 1 | |a Ortega, Belén Padilla |e investigator |4 oth | |
| 700 | 1 | |a Vidaurreta, Paloma Gijón |e investigator |4 oth | |
| 700 | 1 | |a Vidal, Francesc |e investigator |4 oth | |
| 700 | 1 | |a Peraire, Joaquín |e investigator |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |t HIV medicine |d 1999 |g 14(2013), 5 vom: 21. Mai, Seite 273-83 |w (DE-627)NLM116282541 |x 1468-1293 |7 nnns |
| 773 | 1 | 8 | |g volume:14 |g year:2013 |g number:5 |g day:21 |g month:05 |g pages:273-83 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/hiv.12001 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 14 |j 2013 |e 5 |b 21 |c 05 |h 273-83 | ||