The role of circadian clocks in metabolic disease
The circadian clock is a highly conserved timing system, resonating physiological processes to 24-hour environmental cycles. Circadian misalignment is emerging as a risk factor of metabolic disease. The molecular clock resides in all metabolic tissues, the dysfunction of which is associated with perturbed energy metabolism. In this article, we will review current knowledge about molecular mechanisms of the circadian clock and the role of clocks in the physiology and pathophysiology of metabolic tissues.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2012 |
|---|---|
| Erschienen: |
2012 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:85 |
|---|---|
| Enthalten in: |
The Yale journal of biology and medicine - 85(2012), 3 vom: 30. Sept., Seite 387-401 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Li, Min-Dian [VerfasserIn] |
|---|
| Themen: |
ARNTL Transcription Factors |
|---|
| Anmerkungen: |
Date Completed 07.02.2013 Date Revised 21.10.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| Förderinstitution / Projekttitel: |
|
|---|
| PPN (Katalog-ID): |
NLM221343075 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM221343075 | ||
| 003 | DE-627 | ||
| 005 | 20231224051625.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231224s2012 xx |||||o 00| ||eng c | ||
| 028 | 5 | 2 | |a pubmed24n0737.xml |
| 035 | |a (DE-627)NLM221343075 | ||
| 035 | |a (NLM)23012586 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Li, Min-Dian |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The role of circadian clocks in metabolic disease |
| 264 | 1 | |c 2012 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 07.02.2013 | ||
| 500 | |a Date Revised 21.10.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The circadian clock is a highly conserved timing system, resonating physiological processes to 24-hour environmental cycles. Circadian misalignment is emerging as a risk factor of metabolic disease. The molecular clock resides in all metabolic tissues, the dysfunction of which is associated with perturbed energy metabolism. In this article, we will review current knowledge about molecular mechanisms of the circadian clock and the role of clocks in the physiology and pathophysiology of metabolic tissues | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a circadian clocks | |
| 650 | 4 | |a metabolic disease | |
| 650 | 4 | |a metabolism | |
| 650 | 7 | |a ARNTL Transcription Factors |2 NLM | |
| 650 | 7 | |a Glucose |2 NLM | |
| 650 | 7 | |a IY9XDZ35W2 |2 NLM | |
| 700 | 1 | |a Li, Chao-Min |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Zhong |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The Yale journal of biology and medicine |d 1928 |g 85(2012), 3 vom: 30. Sept., Seite 387-401 |w (DE-627)NLM000296252 |x 1551-4056 |7 nnns |
| 773 | 1 | 8 | |g volume:85 |g year:2012 |g number:3 |g day:30 |g month:09 |g pages:387-401 |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 85 |j 2012 |e 3 |b 30 |c 09 |h 387-401 | ||