Autologous bone marrow derived mononuclear cells combined with β-tricalcium phosphate and absorbable atelocollagen for a treatment of aneurysmal bone cyst of the humerus in child
Aneurysmal bone cyst is a benign, locally destructive lesion of bone. Based on progressive cortical thinning pathological fractures are common, and are often the presenting feature. Despite the long experience of orthopaedists, radiologists and pathologists with aneurysmal bone cyst there is limited knowledge regarding the cause of the lesion and optimal treatment. Common methods of treatment vary considerably in the literature, particularly in children. A large variety of bone substitutes have been used to fill the cystic lesions. To date there has been no graft material which can be regarded as completely satisfactory. Our experience with freshly isolated autologous bone marrow derived mononuclear cells combined with β-tricalcium phosphate and absorbable atelocollagen for bone formation is presented. The concept of this treatment is based on stimulation of natural events continuously present in living bone appear to be a reasonable and beneficial alternative to promote healing of bone cysts and offering both osteoinduction and osteoconductive features.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2013 |
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| Erschienen: |
2013 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
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| Enthalten in: |
Journal of biomaterials applications - 28(2013), 3 vom: 01. Sept., Seite 343-53 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Bulgin, Dmitry [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 01.04.2014 Date Revised 27.08.2013 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1177/0885328212451047 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM218579799 |
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| 245 | 1 | 0 | |a Autologous bone marrow derived mononuclear cells combined with β-tricalcium phosphate and absorbable atelocollagen for a treatment of aneurysmal bone cyst of the humerus in child |
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| 500 | |a Date Revised 27.08.2013 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Aneurysmal bone cyst is a benign, locally destructive lesion of bone. Based on progressive cortical thinning pathological fractures are common, and are often the presenting feature. Despite the long experience of orthopaedists, radiologists and pathologists with aneurysmal bone cyst there is limited knowledge regarding the cause of the lesion and optimal treatment. Common methods of treatment vary considerably in the literature, particularly in children. A large variety of bone substitutes have been used to fill the cystic lesions. To date there has been no graft material which can be regarded as completely satisfactory. Our experience with freshly isolated autologous bone marrow derived mononuclear cells combined with β-tricalcium phosphate and absorbable atelocollagen for bone formation is presented. The concept of this treatment is based on stimulation of natural events continuously present in living bone appear to be a reasonable and beneficial alternative to promote healing of bone cysts and offering both osteoinduction and osteoconductive features | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Aneurysmal bone cyst | |
| 650 | 4 | |a absorbable atelocollagen | |
| 650 | 4 | |a bone marrow derived mononuclear cells | |
| 650 | 4 | |a bone regeneration | |
| 650 | 4 | |a mesenchymal stem cells | |
| 650 | 4 | |a β-tricalcium phosphate | |
| 650 | 7 | |a Calcium Phosphates |2 NLM | |
| 650 | 7 | |a atelocollagen |2 NLM | |
| 650 | 7 | |a beta-tricalcium phosphate |2 NLM | |
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| 700 | 1 | |a Irha, Ernest |e verfasserin |4 aut | |
| 700 | 1 | |a Hodzic, Enes |e verfasserin |4 aut | |
| 700 | 1 | |a Nemec, Boris |e verfasserin |4 aut | |
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