Primary extranodal non-Hodgkin's lymphoma of the vagina : a case report and a review of the literature
Copyright © 2012 S. Karger AG, Basel..
Primary lymphoma of the female genital tract is very rare. We report the case of a 36-year-old woman who was referred to our hospital because of an indeterminate Pap smear test. The colposcopy showed a thickening of the posterior vaginal wall and various irregular ulcerated nodular lesions. Histological examination, immunohistochemistry and the staging procedures were conclusive of diffuse large B-cell lymphoma of the vagina, stage IEA. Complete remission was achieved after 6 cycles of immunopolychemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). No relapse has occurred during a follow-up of 71 months. Moreover, we reviewed the 62 previously reported cases of primary extranodal non-Hodgkin's lymphoma of the vagina, focusing on clinicopathological and therapeutic aspects, to better characterize this unusual disease.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2012 |
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| Erschienen: |
2012 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:128 |
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| Enthalten in: |
Acta haematologica - 128(2012), 1 vom: 15., Seite 33-8 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Guastafierro, Salvatore [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-Inflammatory Agents |
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| Anmerkungen: |
Date Completed 10.09.2012 Date Revised 04.07.2012 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1159/000337336 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM217773745 |
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| 245 | 1 | 0 | |a Primary extranodal non-Hodgkin's lymphoma of the vagina |b a case report and a review of the literature |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2012 S. Karger AG, Basel. | ||
| 520 | |a Primary lymphoma of the female genital tract is very rare. We report the case of a 36-year-old woman who was referred to our hospital because of an indeterminate Pap smear test. The colposcopy showed a thickening of the posterior vaginal wall and various irregular ulcerated nodular lesions. Histological examination, immunohistochemistry and the staging procedures were conclusive of diffuse large B-cell lymphoma of the vagina, stage IEA. Complete remission was achieved after 6 cycles of immunopolychemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). No relapse has occurred during a follow-up of 71 months. Moreover, we reviewed the 62 previously reported cases of primary extranodal non-Hodgkin's lymphoma of the vagina, focusing on clinicopathological and therapeutic aspects, to better characterize this unusual disease | ||
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| 700 | 1 | |a Rossiello, Raffaele |e verfasserin |4 aut | |
| 700 | 1 | |a Falcone, Umberto |e verfasserin |4 aut | |
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