Host glycans and antigen presentation

Copyright © 2012 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved..

The cell-mediated adaptive immune response depends upon the activation of T cells via recognition of antigen in the context of a major histocompatibility complex (MHC) molecule. Although studies have shown that alterations in T cell receptor glycosylation reduces the activation threshold, the data on MHC is far less definitive. Here, we discuss the data on MHC glycosylation and the role the glycans might play during the adaptive host response.

Medienart:

E-Artikel

Erscheinungsjahr:

2012

Erschienen:

2012

Enthalten in:

Zur Gesamtaufnahme - volume:14

Enthalten in:

Microbes and infection - 14(2012), 11 vom: 29. Sept., Seite 894-903

Sprache:

Englisch

Beteiligte Personen:

Ryan, Sean O [VerfasserIn]
Cobb, Brian A [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Polysaccharides
Research Support, N.I.H., Extramural
Review

Anmerkungen:

Date Completed 28.03.2013

Date Revised 21.10.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.micinf.2012.04.010

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM217735282